SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jca'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3jca INTEGRASE
(Mouse
mammary
tumor
virus) 		4 / 6 GLN A 154
ASP A  65
VAL A  82
HIS A 161
 None
 1.39A 1ekjG-3jcaA:
undetectable
1ekjH-3jcaA:
undetectable		 1ekjG-3jcaA:
20.30
1ekjH-3jcaA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 3jca INTEGRASE
(Mouse
mammary
tumor
virus) 		5 / 9 GLY A 227
ILE C 261
ALA C 243
VAL C 256
PHE C 260
 None
 1.22A 2drdA-3jcaA:
undetectable		 2drdA-3jcaA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3jca INTEGRASE
(Mouse
mammary
tumor
virus) 		3 / 3 GLN A 117
THR A  84
TRP A 255
 None
 1.15A 2rctA-3jcaA:
undetectable		 2rctA-3jcaA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 3jca INTEGRASE
(Mouse
mammary
tumor
virus) 		4 / 8 ASP A  65
ASP A 122
PRO A 148
TYR A 149
 None
 0.92A 3oyaA-3jcaA:
11.3		 3oyaA-3jcaA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 3jca INTEGRASE
(Mouse
mammary
tumor
virus) 		5 / 11 ALA A 124
ASP A 122
THR A  99
LEU A 106
ILE A 132
 None
 1.05A 3tqbA-3jcaA:
undetectable		 3tqbA-3jcaA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3jca INTEGRASE
(Mouse
mammary
tumor
virus) 		3 / 3 ALA A  91
GLN A 154
GLY A 153
 None
 0.56A 4odoC-3jcaA:
undetectable		 4odoC-3jcaA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3jca INTEGRASE
(Mouse
mammary
tumor
virus) 		3 / 3 GLY A 146
THR A 121
ASN A 123
 None
 0.65A 5odiG-3jcaA:
undetectable		 5odiG-3jcaA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3jca INTEGRASE
(Mouse
mammary
tumor
virus) 		3 / 3 HIS A 193
ASN A 192
LEU A 191
 None
 0.84A 6f7lB-3jcaA:
undetectable		 6f7lB-3jcaA:
21.46