SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jci'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3jci CAPSID PROTEIN
(Porcine
circovirus
2) 		3 / 3 ALA A 122
VAL A 142
TRP A  67
 None
 0.99A 1tkqA-3jciA:
undetectable		 1tkqA-3jciA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 3jci CAPSID PROTEIN
(Porcine
circovirus
2) 		3 / 3 TYR A 141
VAL A 130
THR A 200
 None
 0.63A 2ygnA-3jciA:
undetectable		 2ygnA-3jciA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3jci CAPSID PROTEIN
(Porcine
circovirus
2) 		5 / 11 HIS A 157
VAL A 103
PHE A  74
THR A 121
THR A 200
 None
 1.18A 3hs4A-3jciA:
undetectable		 3hs4A-3jciA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3jci CAPSID PROTEIN
(Porcine
circovirus
2) 		5 / 11 HIS A 157
VAL A 103
PHE A  74
THR A 121
THR A 200
 None
 1.08A 3ml5A-3jciA:
undetectable		 3ml5A-3jciA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3jci CAPSID PROTEIN
(Porcine
circovirus
2) 		3 / 3 ASP A 127
ARG A  73
ASP A 168
 None
 0.72A 4fp9A-3jciA:
undetectable		 4fp9A-3jciA:
20.60