SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jcu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 PHE G  58
TYR G  35
LEU G  36
GLY G  42
 CLA  G 602 ( 4.9A)
None
CLA  G 602 (-4.1A)
CLA  G 602 (-4.4A)
 1.01A 1rmtC-3jcuG:
undetectable		 1rmtC-3jcuG:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 TYR O 234
PRO O 232
THR O 163
THR O 166
 None
 1.24A 1ymxB-3jcuO:
undetectable		 1ymxB-3jcuO:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 7 LEU Q 145
VAL Q 144
VAL Q  92
ASP Q  88
 None
 1.04A 1yrdA-3jcuQ:
undetectable		 1yrdA-3jcuQ:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 LYS Q   1
GLY Q   8
PRO Q   9
 None
 1.01A 2hreB-3jcuQ:
undetectable		 2hreB-3jcuQ:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 GLU G  65
LEU G 155
TYR G 156
MET G 188
ARG G 185
 CLA  G 602 (-2.7A)
None
CLA  G 610 (-3.9A)
CLA  G 602 ( 3.3A)
CLA  G 602 (-3.2A)
 1.43A 2jj8B-3jcuG:
undetectable		 2jj8B-3jcuG:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN 26
KD (CP26)
(Spinacia
oleracea) 		4 / 6 ARG S 194
PRO S  54
GLY S  55
TRP S  26
 CLA  S 602 (-3.1A)
None
None
CLA  S 611 ( 3.9A)
 0.74A 2y7pA-3jcuS:
undetectable		 2y7pA-3jcuS:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 ARG G 185
PRO G  41
GLY G  42
TRP G  16
 CLA  G 602 (-3.2A)
None
CLA  G 602 (-4.4A)
CLA  G 611 ( 3.7A)
 0.82A 2y7pA-3jcuG:
undetectable		 2y7pA-3jcuG:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 LEU Q 145
VAL Q 144
VAL Q  92
ASP Q  88
 None
 0.97A 2zawA-3jcuQ:
undetectable		 2zawA-3jcuQ:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 7 LEU Q 145
VAL Q 144
VAL Q  92
ASP Q  88
 None
 1.06A 2zaxA-3jcuQ:
undetectable		 2zaxA-3jcuQ:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 7 GLY P  89
ALA P 111
ALA P 109
VAL P 131
 None
 0.70A 3a2qA-3jcuP:
undetectable		 3a2qA-3jcuP:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 LEU Q 145
VAL Q 144
VAL Q  92
ASP Q  88
 None
 1.13A 3fwgA-3jcuQ:
undetectable		 3fwgA-3jcuQ:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
OXYGEN-EVOLVING
ENHANCER PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea;
Spinacia
oleracea) 		5 / 12 GLU P  78
LEU Q  13
SER Q  14
SER P 116
GLU P 115
 None
 1.00A 3g2oA-3jcuP:
undetectable		 3g2oA-3jcuP:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN 29
KD (CP29)
(Spinacia
oleracea) 		5 / 12 PHE R 211
GLY R 207
ALA R 204
GLY R 109
LEU R 108
 LUT  R 620 (-3.8A)
LUT  R 620 (-3.9A)
LUT  R 620 (-3.5A)
CLA  R 604 (-3.2A)
CLA  R 604 (-4.4A)
 1.01A 3hs6B-3jcuR:
undetectable		 3hs6B-3jcuR:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 LYS Q  96
PRO Q  97
LEU Q 104
SER Q 103
 None
 1.25A 3ijxH-3jcuQ:
undetectable		 3ijxH-3jcuQ:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 7 TYR P  49
VAL P  46
ASN P  22
GLY P  23
 None
 1.11A 3kmoB-3jcuP:
undetectable		 3kmoB-3jcuP:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 GLY G 202
TRP G  97
VAL G  96
 None
 0.74A 3n62B-3jcuG:
undetectable		 3n62B-3jcuG:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 GLY G 202
TRP G  97
VAL G  96
 None
 0.73A 3n65B-3jcuG:
undetectable		 3n65B-3jcuG:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 GLY G 202
TRP G  97
VAL G  96
 None
 0.74A 3n66B-3jcuG:
undetectable		 3n66B-3jcuG:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 THR P  56
SER P  57
ARG P 167
 None
 0.55A 3phnA-3jcuP:
undetectable		 3phnA-3jcuP:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 LEU Q 145
VAL Q 144
VAL Q  92
ASP Q  88
 None
 1.11A 4ek1A-3jcuQ:
undetectable		 4ek1A-3jcuQ:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 LEU P  88
SER P 110
LEU P 132
LEU P  81
 None
 1.17A 4n09B-3jcuP:
undetectable		 4n09B-3jcuP:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 GLY G 202
TRP G  97
VAL G  96
 None
 0.74A 5vuoB-3jcuG:
undetectable		 5vuoB-3jcuG:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 PRO O 175
GLY O 174
THR O 130
LYS O 132
 None
 1.04A 5x23A-3jcuO:
undetectable		 5x23A-3jcuO:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 PRO O 175
GLY O 174
THR O 130
LYS O 132
 None
 1.03A 5xxiA-3jcuO:
undetectable		 5xxiA-3jcuO:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 GLY P 138
ASP P 137
ARG P 134
GLN P  91
 None
 1.24A 5zrfB-3jcuP:
undetectable		 5zrfB-3jcuP:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		6 / 10 PHE O 301
LEU O 285
THR O 284
ILE O 321
PHE O 134
ILE O 213
 None
 1.41A 6ebpB-3jcuO:
undetectable		 6ebpB-3jcuO:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		6 / 10 PHE O 301
LEU O 285
THR O 284
ILE O 321
PHE O 134
ILE O 213
 None
 1.40A 6ebpC-3jcuO:
undetectable		 6ebpC-3jcuO:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		6 / 11 PHE O 301
LEU O 285
THR O 284
ILE O 321
PHE O 134
ILE O 213
 None
 1.41A 6ebzA-3jcuO:
undetectable		 6ebzA-3jcuO:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		6 / 11 PHE O 301
LEU O 285
THR O 284
ILE O 321
PHE O 134
ILE O 213
 None
 1.39A 6ebzB-3jcuO:
undetectable		 6ebzB-3jcuO:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		6 / 11 PHE O 301
LEU O 285
THR O 284
ILE O 321
PHE O 134
ILE O 213
 None
 1.39A 6ebzC-3jcuO:
undetectable		 6ebzC-3jcuO:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
(Spinacia
oleracea) 		6 / 11 PHE O 301
LEU O 285
THR O 284
ILE O 321
PHE O 134
ILE O 213
 None
 1.43A 6ebzD-3jcuO:
undetectable		 6ebzD-3jcuO:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3jcu CHLOROPHYLL A-B
BINDING PROTEIN 26
KD (CP26)
(Spinacia
oleracea) 		3 / 3 HIS S 221
ASN S 229
LEU S 230
 CLA  S 614 ( 3.4A)
CLA  S 614 ( 3.7A)
CLA  S 613 (-3.7A)
 0.89A 6f7lB-3jcuS:
undetectable		 6f7lB-3jcuS:
22.54