SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jcx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 3jcx FAB E HEAVY CHAIN
(Rattus
norvegicus) 		3 / 3 ALA H 192
VAL H 135
TRP H 213
 None
 0.97A 1av2A-3jcxH:
undetectable
1av2B-3jcxH:
undetectable		 1av2A-3jcxH:
9.35
1av2B-3jcxH:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 3jcx FAB E LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 ASP L  32
PHE L  71
ASN L  51
 None
 0.89A 1sg9B-3jcxL:
undetectable		 1sg9B-3jcxL:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 3jcx FAB E HEAVY CHAIN
FAB E LIGHT CHAIN
(Rattus
norvegicus) 		4 / 4 THR L  95
VAL L  27
GLY H 207
THR H 205
 None
 1.09A 3cflA-3jcxL:
undetectable		 3cflA-3jcxL:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3jcx FAB E LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 MET L  76
GLN L  77
ARG L  59
 None
 0.93A 5ewzB-3jcxL:
undetectable		 5ewzB-3jcxL:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3jcx FAB E LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 MET L  76
GLN L  77
ARG L  59
 None
 0.93A 5m35B-3jcxL:
undetectable		 5m35B-3jcxL:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3jcx FAB E LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 MET L  76
GLN L  77
ARG L  59
 None
 0.96A 5m36A-3jcxL:
undetectable		 5m36A-3jcxL:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3jcx FAB E LIGHT CHAIN
(Rattus
norvegicus) 		5 / 12 LEU L  45
PHE L  71
ALA L  82
ALA L  78
GLY L  14
 None
 1.10A 5veuA-3jcxL:
undetectable		 5veuA-3jcxL:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3jcx FAB E HEAVY CHAIN
(Rattus
norvegicus) 		4 / 5 HIS H 136
ASP H 157
GLY H 150
ASN H 165
 None
 1.42A 5x7pB-3jcxH:
undetectable		 5x7pB-3jcxH:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3jcx FAB E LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 MET L  76
GLN L  77
ARG L  59
 None
 0.99A 6fn9A-3jcxL:
undetectable		 6fn9A-3jcxL:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3jcx FAB E LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 MET L  76
GLN L  77
ARG L  59
 None
 0.94A 6fnaB-3jcxL:
undetectable		 6fnaB-3jcxL:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3jcx FAB E LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 MET L  76
GLN L  77
ARG L  59
 None
 0.98A 6fnbA-3jcxL:
undetectable		 6fnbA-3jcxL:
18.64