SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jd5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 HIS K 149
SER K 104
LEU K 110
GLY K 146
 None
 1.03A 1a4lB-3jd5K:
undetectable		 1a4lB-3jd5K:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 ILE B 131
ALA B 122
LEU B 118
LEU B 185
ILE B 183
 None
 1.04A 1cd2A-3jd5B:
undetectable		 1cd2A-3jd5B:
18.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 3jd5 28S RIBOSOMAL
PROTEIN S10,
MITOCHONDRIAL
PENTATRICOPEPTIDE
REPEAT
DOMAIN-CONTAINING
PROTEIN 3,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		3 / 3 ALA J 153
VAL J 155
TRP o  65
 None
 1.02A 1gmkA-3jd5J:
undetectable
1gmkB-3jd5J:
undetectable		 1gmkA-3jd5J:
31.25
1gmkB-3jd5J:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 3jd5 28S RIBOSOMAL
PROTEIN S10,
MITOCHONDRIAL
PENTATRICOPEPTIDE
REPEAT
DOMAIN-CONTAINING
PROTEIN 3,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		3 / 3 ALA J 153
VAL J 155
TRP o  65
 None
 0.92A 1gmkC-3jd5J:
undetectable
1gmkD-3jd5J:
undetectable		 1gmkC-3jd5J:
31.25
1gmkD-3jd5J:
31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S23,
MITOCHONDRIAL
(Bos
taurus) 		5 / 6 PHE B  62
PHE B 126
GLU B  54
LEU B  56
VAL b  34
 None
 1.46A 1hk1A-3jd5B:
2.7		 1hk1A-3jd5B:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 ILE K 100
ALA K  93
LYS K 166
ILE K 178
THR K  98
 None
 1.17A 1jolA-3jd5K:
undetectable		 1jolA-3jd5K:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 3jd5 28S RIBOSOMAL
PROTEIN S7,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 GLN I 308
GLU I 311
MET G 111
ALA G 107
 G  A 811 ( 4.4A)
None
None
U  A 719 ( 4.2A)
 1.21A 1linA-3jd5I:
undetectable		 1linA-3jd5I:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S6,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S18C,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		3 / 3 ASP F  67
LYS F  95
ARG R 114
 None
U  A 382 ( 2.8A)
C  A 380 ( 3.8A)
 1.12A 1ra8A-3jd5F:
undetectable		 1ra8A-3jd5F:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 1v54A-3jd5j:
undetectable
1v54C-3jd5j:
undetectable		 1v54A-3jd5j:
15.59
1v54C-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.10A 1v54N-3jd5j:
undetectable
1v54P-3jd5j:
undetectable		 1v54N-3jd5j:
15.59
1v54P-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 1v55A-3jd5j:
undetectable
1v55C-3jd5j:
undetectable		 1v55A-3jd5j:
15.59
1v55C-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S22,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 GLN a 289
ILE a 288
TYR a 348
 None
 0.65A 1vifA-3jd5a:
undetectable		 1vifA-3jd5a:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 3jd5 28S RIBOSOMAL
PROTEIN S27,
MITOCHONDRIAL
(Bos
taurus) 		5 / 9 THR e 111
GLU e  84
HIS e  87
ALA e  88
LEU e  92
 None
 1.47A 2azqA-3jd5e:
undetectable		 2azqA-3jd5e:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3jd5 28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 ARG I 276
SER I 338
ARG I 345
GLN I 308
 G  A 785 ( 3.4A)
G  A 811 ( 3.3A)
None
G  A 811 ( 4.4A)
 1.29A 2c8aA-3jd5I:
undetectable		 2c8aA-3jd5I:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 ILE B 131
ALA B 122
LEU B 118
LEU B 185
ILE B 183
 None
 1.06A 2cd2A-3jd5B:
undetectable		 2cd2A-3jd5B:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3jd5 28S RIBOSOMAL
PROTEIN S22,
MITOCHONDRIAL
(Bos
taurus) 		5 / 10 TYR a 348
ALA a 347
ILE a 285
GLU a 342
ILE a 341
 None
 1.37A 2dm6A-3jd5a:
undetectable
2dm6B-3jd5a:
undetectable		 2dm6A-3jd5a:
20.10
2dm6B-3jd5a:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 2dyrA-3jd5j:
undetectable
2dyrC-3jd5j:
undetectable		 2dyrA-3jd5j:
15.59
2dyrC-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 2dyrN-3jd5j:
undetectable
2dyrP-3jd5j:
undetectable		 2dyrN-3jd5j:
15.59
2dyrP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 2eijA-3jd5j:
undetectable
2eijC-3jd5j:
undetectable		 2eijA-3jd5j:
15.59
2eijC-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 2eijN-3jd5j:
undetectable
2eijP-3jd5j:
undetectable		 2eijN-3jd5j:
15.59
2eijP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.10A 2eikA-3jd5j:
undetectable
2eikC-3jd5j:
undetectable		 2eikA-3jd5j:
15.59
2eikC-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 2eilA-3jd5j:
undetectable
2eilC-3jd5j:
undetectable		 2eilA-3jd5j:
15.59
2eilC-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 2eilN-3jd5j:
undetectable
2eilP-3jd5j:
undetectable		 2eilN-3jd5j:
15.59
2eilP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 3jd5 28S RIBOSOMAL
PROTEIN S22,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 ALA a 331
ILE a 341
ILE a 280
ASP a 281
 None
 1.00A 2h4jA-3jd5a:
undetectable		 2h4jA-3jd5a:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
PENTATRICOPEPTIDE
REPEAT
DOMAIN-CONTAINING
PROTEIN 3,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 TRP E 141
ALA o 117
LEU E 144
ALA o 116
 None
 1.32A 2jstA-3jd5E:
undetectable
2jstB-3jd5E:
undetectable		 2jstA-3jd5E:
9.85
2jstB-3jd5E:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIV_A_T3A933_1
(ANDROGEN RECEPTOR)		 3jd5 28S RIBOSOMAL
PROTEIN S25,
MITOCHONDRIAL
(Bos
taurus) 		5 / 9 PRO c  53
ILE c  52
PHE c  50
GLY c  43
GLU c  97
 None
 1.20A 2pivA-3jd5c:
undetectable		 2pivA-3jd5c:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 GLU K  84
PRO K  70
ILE K  69
GLY K  71
 None
 1.18A 2qeuA-3jd5K:
undetectable
2qeuC-3jd5K:
undetectable		 2qeuA-3jd5K:
21.60
2qeuC-3jd5K:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA155_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 3jd5 28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		4 / 5 ARG k  88
GLY k  96
PRO I 133
PHE I 132
 None
 1.45A 2rezA-3jd5k:
undetectable		 2rezA-3jd5k:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 ILE B 221
PHE B 184
PHE B 133
ALA B 201
ILE B 131
 None
 1.17A 2rlcA-3jd5B:
undetectable		 2rlcA-3jd5B:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S23,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		4 / 8 PRO B 207
THR B 222
VAL B 209
PRO b  40
 None
 0.97A 2v32C-3jd5B:
undetectable
2v32D-3jd5B:
undetectable		 2v32C-3jd5B:
19.93
2v32D-3jd5B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S27,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 ALA e  88
THR e 111
ILE e 109
PRO e 139
LEU e 104
 None
 1.12A 2w3bA-3jd5e:
undetectable		 2w3bA-3jd5e:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 GLY K 171
GLY K 167
GLN K 132
THR K 133
 None
 0.62A 2wd9B-3jd5K:
undetectable		 2wd9B-3jd5K:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TYR I 152
PHE B 160
ALA B 197
ALA B 201
 None
 0.61A 2wx2B-3jd5I:
undetectable		 2wx2B-3jd5I:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.10A 2y69C-3jd5j:
undetectable
2y69N-3jd5j:
undetectable
2y69P-3jd5j:
undetectable		 2y69C-3jd5j:
18.80
2y69N-3jd5j:
15.59
2y69P-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_1
(HYPOTHETICAL PROTEIN)		 3jd5 28S RIBOSOMAL
PROTEIN S27,
MITOCHONDRIAL
(Bos
taurus) 		4 / 4 GLU e 174
ASP e 372
ASP e 140
TYR e 142
 None
 1.40A 2yvlA-3jd5e:
0.0		 2yvlA-3jd5e:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.13A 3abkA-3jd5j:
undetectable
3abkC-3jd5j:
undetectable		 3abkA-3jd5j:
15.59
3abkC-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.09A 3abkN-3jd5j:
undetectable
3abkP-3jd5j:
undetectable		 3abkN-3jd5j:
15.59
3abkP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.14A 3ablA-3jd5j:
undetectable
3ablC-3jd5j:
undetectable
3ablP-3jd5j:
undetectable		 3ablA-3jd5j:
15.59
3ablC-3jd5j:
18.80
3ablP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.14A 3ablC-3jd5j:
undetectable
3ablN-3jd5j:
undetectable
3ablP-3jd5j:
undetectable		 3ablC-3jd5j:
18.80
3ablN-3jd5j:
15.59
3ablP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.07A 3abmA-3jd5j:
undetectable
3abmC-3jd5j:
undetectable
3abmP-3jd5j:
undetectable		 3abmA-3jd5j:
15.59
3abmC-3jd5j:
18.80
3abmP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 3ag3A-3jd5j:
undetectable
3ag3C-3jd5j:
undetectable		 3ag3A-3jd5j:
15.59
3ag3C-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 3ag3N-3jd5j:
undetectable
3ag3P-3jd5j:
undetectable		 3ag3N-3jd5j:
15.59
3ag3P-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3jd5 28S RIBOSOMAL
PROTEIN S23,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 PHE E 218
VAL b  24
LEU b   6
HIS E 277
ALA E 275
 None
None
None
C  A 629 ( 3.7A)
None
 1.43A 3apvB-3jd5E:
undetectable		 3apvB-3jd5E:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 3asnC-3jd5j:
undetectable
3asnN-3jd5j:
undetectable
3asnP-3jd5j:
undetectable		 3asnC-3jd5j:
18.80
3asnN-3jd5j:
15.59
3asnP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 3asoC-3jd5j:
undetectable
3asoN-3jd5j:
undetectable
3asoP-3jd5j:
undetectable		 3asoC-3jd5j:
18.80
3asoN-3jd5j:
15.59
3asoP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3jd5 28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		5 / 11 LEU k  85
ALA I  89
VAL k  83
LEU k 114
GLN I 101
 None
 1.18A 3bszE-3jd5k:
undetectable		 3bszE-3jd5k:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3jd5 28S RIBOSOMAL
PROTEIN S27,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 TYR e 184
GLU e 200
ASP e 195
 None
 0.81A 3bxoA-3jd5e:
undetectable		 3bxoA-3jd5e:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3jd5 28S RIBOSOMAL
PROTEIN S27,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 TYR e 184
GLU e 200
ASP e 195
 None
 0.81A 3bxoB-3jd5e:
undetectable		 3bxoB-3jd5e:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 3jd5 28S RIBOSOMAL
PROTEIN S27,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 ALA e  88
THR e 111
PRO e 139
PHE e 138
LEU e 104
 None
 1.16A 3cl9A-3jd5e:
undetectable		 3cl9A-3jd5e:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		5 / 11 ALA E 319
GLY E 199
ILE E 323
VAL E 245
ALA E 246
 None
 0.79A 3dcmX-3jd5E:
undetectable		 3dcmX-3jd5E:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 3jd5 28S RIBOSOMAL
PROTEIN S22,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 TYR a 249
TYR a 241
GLY a 269
 None
 0.53A 3eteB-3jd5a:
undetectable
3eteD-3jd5a:
undetectable
3eteF-3jd5a:
undetectable		 3eteB-3jd5a:
23.46
3eteD-3jd5a:
23.46
3eteF-3jd5a:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_A_PXLA313_1
(PYRIDOXAL KINASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		4 / 4 SER B 141
HIS B 156
THR I 153
VAL B 134
 None
 1.47A 3fhxA-3jd5B:
undetectable		 3fhxA-3jd5B:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3jd5 28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL
PENTATRICOPEPTIDE
REPEAT
DOMAIN-CONTAINING
PROTEIN 3,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 SER k  81
ASP o  91
ASP o  81
TYR o 522
 None
 0.96A 3havA-3jd5k:
undetectable		 3havA-3jd5k:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3jd5 28S RIBOSOMAL
PROTEIN S25,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 LEU c 155
PRO c 156
LEU c 159
 None
 0.52A 3hcrA-3jd5c:
undetectable		 3hcrA-3jd5c:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3jd5 28S RIBOSOMAL
PROTEIN S15,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S25,
MITOCHONDRIAL
(Bos
taurus) 		4 / 4 PRO c  72
TYR Q 105
GLY Q 102
THR O 172
 None
 1.17A 3ib0A-3jd5c:
undetectable		 3ib0A-3jd5c:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 ALA B 117
LEU B 241
GLN B 243
VAL B 211
THR B 121
 None
 1.19A 3ix9B-3jd5B:
undetectable		 3ix9B-3jd5B:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TYR I 152
PHE B 160
ALA B 197
ALA B 201
 None
 0.72A 3khmA-3jd5I:
undetectable		 3khmA-3jd5I:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3jd5 28S RIBOSOMAL
PROTEIN S10,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL
(Bos
taurus) 		4 / 6 VAL k 196
LEU J 180
ILE k 153
LEU k 231
 None
 0.98A 3kk6A-3jd5k:
undetectable		 3kk6A-3jd5k:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
(Bos
taurus) 		4 / 6 LEU B 143
SER B 141
PHE B 140
PHE B 184
 None
 0.90A 3ko0S-3jd5B:
undetectable		 3ko0S-3jd5B:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 HIS B  79
VAL B  78
VAL B  70
ALA B 111
 None
 0.93A 3kp6B-3jd5B:
undetectable		 3kp6B-3jd5B:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 LEU B 114
VAL B 211
VAL B  78
GLY B 227
PRO B 224
 None
 1.26A 3mecA-3jd5B:
undetectable		 3mecA-3jd5B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3jd5 28S RIBOSOMAL
PROTEIN S18C,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 ILE R 112
VAL R  78
LEU R  81
SER R  82
 None
 0.68A 3r9vA-3jd5R:
undetectable
3r9vB-3jd5R:
undetectable		 3r9vA-3jd5R:
17.45
3r9vB-3jd5R:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 3jd5 28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL
(Bos
taurus) 		5 / 9 LEU k 286
THR k 288
VAL k 291
ILE k 264
PHE k 269
 None
 1.10A 3tbgD-3jd5k:
undetectable		 3tbgD-3jd5k:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3jd5 28S RIBOSOMAL
PROTEIN S25,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 PRO c  74
ASP c  89
GLU c  91
 None
 0.87A 3v4tC-3jd5c:
undetectable		 3v4tC-3jd5c:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3jd5 28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 SER I 333
GLY I 334
GLN I 340
 None
 0.61A 3v4tH-3jd5I:
undetectable		 3v4tH-3jd5I:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 3wg7A-3jd5j:
undetectable
3wg7C-3jd5j:
undetectable
3wg7P-3jd5j:
undetectable		 3wg7A-3jd5j:
15.59
3wg7C-3jd5j:
18.80
3wg7P-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 3x2qA-3jd5j:
undetectable
3x2qC-3jd5j:
undetectable
3x2qP-3jd5j:
undetectable		 3x2qA-3jd5j:
15.59
3x2qC-3jd5j:
18.80
3x2qP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.13A 3x2qC-3jd5j:
undetectable
3x2qN-3jd5j:
undetectable
3x2qP-3jd5j:
undetectable		 3x2qC-3jd5j:
18.80
3x2qN-3jd5j:
15.59
3x2qP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		3 / 3 ARG B 136
ASP I 217
GLN I 216
 A  A 644 ( 3.7A)
A  A 641 ( 3.1A)
A  A 641 ( 3.7A)
 0.89A 4azsA-3jd5B:
undetectable		 4azsA-3jd5B:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 ARG E 128
ARG E 176
TRP E 179
 None
 1.26A 4b7nA-3jd5E:
undetectable		 4b7nA-3jd5E:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 ARG E 128
ARG E 176
TRP E 179
 None
 1.30A 4cpzC-3jd5E:
undetectable		 4cpzC-3jd5E:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 ARG E 128
ARG E 176
TRP E 179
 None
 1.30A 4cpzE-3jd5E:
undetectable		 4cpzE-3jd5E:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 ARG E 128
ARG E 176
TRP E 179
 None
 1.25A 4cpzF-3jd5E:
undetectable		 4cpzF-3jd5E:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 ARG E 128
ARG E 176
TRP E 179
 None
 1.24A 4cpzG-3jd5E:
undetectable		 4cpzG-3jd5E:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 ARG E 128
ARG E 176
TRP E 179
 None
 1.22A 4cpzH-3jd5E:
undetectable		 4cpzH-3jd5E:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 TYR j  34
ARG j  43
HIS j  45
 A  A  60 ( 4.4A)
C  A  61 ( 3.8A)
None
 1.10A 4fubA-3jd5j:
undetectable		 4fubA-3jd5j:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 3jd5 28S RIBOSOMAL
PROTEIN S31,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 VAL h 345
MET h 342
GLU h 343
LEU h 329
 None
 1.33A 4hojA-3jd5h:
undetectable		 4hojA-3jd5h:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 3jd5 28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 LEU I 346
MET I 364
LEU I 369
ILE I 257
LEU I 352
 None
 1.28A 4j24C-3jd5I:
undetectable		 4j24C-3jd5I:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 3jd5 28S RIBOSOMAL
PROTEIN S15,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 ARG O 224
LYS O 221
LYS O 220
 C  A 124 ( 3.9A)
G  A 126 ( 3.8A)
None
 1.44A 4k50E-3jd5O:
0.5		 4k50E-3jd5O:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 3jd5 28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 LYS k  79
PRO k  80
SER k  81
 None
 0.44A 4k50I-3jd5k:
undetectable		 4k50I-3jd5k:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 3jd5 28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 HIS I 148
TRP I 140
SER I 160
 None
 1.03A 4lrhD-3jd5I:
undetectable		 4lrhD-3jd5I:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3jd5 28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 LEU k 207
ILE k 209
ARG k 199
 None
 0.63A 4mk4B-3jd5k:
undetectable		 4mk4B-3jd5k:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j 139
TRP j  85
TRP j  95
LEU j  97
 None
 1.27A 4nsbA-3jd5j:
undetectable		 4nsbA-3jd5j:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		5 / 11 ILE K 100
ALA K  93
LYS K 166
ILE K 178
THR K  98
 None
 1.22A 4qi9C-3jd5K:
undetectable		 4qi9C-3jd5K:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3jd5 28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S25,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 LEU Q  40
VAL c  48
TYR c  57
ARG Q  29
 None
 1.11A 4r7iA-3jd5Q:
undetectable		 4r7iA-3jd5Q:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3jd5 28S RIBOSOMAL
PROTEIN S22,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 LEU a 326
VAL a 293
ASP a 294
 None
 0.57A 4y8wC-3jd5a:
undetectable		 4y8wC-3jd5a:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3jd5 28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S25,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S26,
MITOCHONDRIAL
(Bos
taurus) 		4 / 6 ASN d 113
THR c  73
PRO c  74
VAL Q  95
 None
 1.07A 4yoaA-3jd5d:
undetectable		 4yoaA-3jd5d:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3jd5 28S RIBOSOMAL
PROTEIN S5,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 TYR E 333
GLY E 424
TYR E 312
GLY E 311
 None
 0.88A 5ayfA-3jd5E:
undetectable		 5ayfA-3jd5E:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 5b1aA-3jd5j:
undetectable
5b1aC-3jd5j:
undetectable
5b1aP-3jd5j:
undetectable		 5b1aA-3jd5j:
15.59
5b1aC-3jd5j:
18.80
5b1aP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 5b1aN-3jd5j:
undetectable
5b1aP-3jd5j:
undetectable		 5b1aN-3jd5j:
15.59
5b1aP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 5b1bA-3jd5j:
undetectable
5b1bC-3jd5j:
undetectable
5b1bP-3jd5j:
undetectable		 5b1bA-3jd5j:
15.59
5b1bC-3jd5j:
18.80
5b1bP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.13A 5b1bN-3jd5j:
undetectable
5b1bP-3jd5j:
undetectable		 5b1bN-3jd5j:
15.59
5b1bP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 5b3sA-3jd5j:
undetectable
5b3sC-3jd5j:
undetectable
5b3sP-3jd5j:
undetectable		 5b3sA-3jd5j:
15.59
5b3sC-3jd5j:
18.80
5b3sP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		3 / 3 ASP I 143
ARG B 127
ARG B 253
 None
 0.97A 5eajB-3jd5I:
undetectable		 5eajB-3jd5I:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 ILE K 100
ALA K  93
LYS K 166
ILE K 178
THR K  98
 None
 1.14A 5hi6A-3jd5K:
undetectable		 5hi6A-3jd5K:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3jd5 28S RIBOSOMAL
PROTEIN S27,
MITOCHONDRIAL
(Bos
taurus) 		5 / 10 ILE e 137
PRO e 139
LEU e 129
LEU e 117
LEU e  92
 None
 1.00A 5ienB-3jd5e:
undetectable		 5ienB-3jd5e:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 5iy5A-3jd5j:
undetectable
5iy5C-3jd5j:
undetectable		 5iy5A-3jd5j:
15.59
5iy5C-3jd5j:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 5iy5C-3jd5j:
undetectable
5iy5N-3jd5j:
undetectable
5iy5P-3jd5j:
undetectable		 5iy5C-3jd5j:
18.56
5iy5N-3jd5j:
15.59
5iy5P-3jd5j:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3jd5 28S RIBOSOMAL
PROTEIN S6,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S26,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		4 / 5 LEU F  42
TYR d 187
LYS d 185
LEU F  65
 None
 1.24A 5ki6A-3jd5F:
undetectable		 5ki6A-3jd5F:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		6 / 12 GLY K 171
GLY K 167
THR K 169
THR K 148
ALA K 137
ALA K 142
 None
 1.41A 5kpcA-3jd5K:
undetectable		 5kpcA-3jd5K:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_2
(ADENOSYLHOMOCYSTEINA
SE)		 3jd5 28S RIBOSOMAL
PROTEIN S27,
MITOCHONDRIAL
(Bos
taurus) 		4 / 4 GLU e 321
THR e 323
GLU e 235
HIS e 245
 None
 1.09A 5utuF-3jd5e:
undetectable		 5utuF-3jd5e:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.10A 5wauA-3jd5j:
undetectable
5wauC-3jd5j:
undetectable
5wauc-3jd5j:
undetectable		 5wauA-3jd5j:
15.59
5wauC-3jd5j:
18.80
5wauc-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 5x1fN-3jd5j:
undetectable
5x1fP-3jd5j:
undetectable		 5x1fN-3jd5j:
15.59
5x1fP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 5xdqA-3jd5j:
undetectable
5xdqC-3jd5j:
undetectable
5xdqP-3jd5j:
undetectable		 5xdqA-3jd5j:
15.59
5xdqC-3jd5j:
18.80
5xdqP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 5xdxC-3jd5j:
undetectable
5xdxN-3jd5j:
undetectable
5xdxP-3jd5j:
undetectable		 5xdxC-3jd5j:
18.49
5xdxN-3jd5j:
15.59
5xdxP-3jd5j:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3jd5 28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		5 / 10 ILE I 293
LEU I 313
PHE I 317
LEU I 346
LEU I 369
 None
 1.11A 5y7pB-3jd5I:
undetectable		 5y7pB-3jd5I:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 3jd5 28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL
(Bos
taurus) 		5 / 10 ILE I 293
LEU I 313
PHE I 317
LEU I 346
LEU I 369
 None
 1.13A 5y7pD-3jd5I:
undetectable		 5y7pD-3jd5I:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3jd5 28S RIBOSOMAL
PROTEIN S10,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 LEU J 143
VAL J  78
VAL J  80
ILE J 160
 None
 0.66A 5y9mA-3jd5J:
undetectable		 5y9mA-3jd5J:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3jd5 28S RIBOSOMAL
PROTEIN S10,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 LEU J 143
VAL J  78
VAL J  80
ILE J 160
 None
 0.73A 5y9mX-3jd5J:
undetectable		 5y9mX-3jd5J:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 3jd5 28S RIBOSOMAL
PROTEIN S23,
MITOCHONDRIAL
(Bos
taurus) 		5 / 11 GLU b 101
GLU b 105
GLY b 122
ALA b 121
ALA b 124
 None
 1.19A 5yk2A-3jd5b:
undetectable		 5yk2A-3jd5b:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3jd5 28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S25,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		3 / 3 LYS Q  41
LEU Q  39
ARG c  11
 G  A 301 ( 4.8A)
None
C  A 282 ( 3.2A)
 0.89A 5yw0A-3jd5Q:
undetectable		 5yw0A-3jd5Q:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 5z84A-3jd5j:
undetectable
5z84C-3jd5j:
undetectable
5z84P-3jd5j:
undetectable		 5z84A-3jd5j:
15.59
5z84C-3jd5j:
18.80
5z84P-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 5z85A-3jd5j:
undetectable
5z85C-3jd5j:
undetectable
5z85P-3jd5j:
undetectable		 5z85A-3jd5j:
15.59
5z85C-3jd5j:
18.80
5z85P-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 5z86A-3jd5j:
undetectable
5z86C-3jd5j:
undetectable
5z86P-3jd5j:
undetectable		 5z86A-3jd5j:
15.59
5z86C-3jd5j:
18.80
5z86P-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.09A 5z86C-3jd5j:
undetectable
5z86N-3jd5j:
undetectable
5z86P-3jd5j:
undetectable		 5z86C-3jd5j:
18.80
5z86N-3jd5j:
15.59
5z86P-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 5zcoA-3jd5j:
undetectable
5zcoC-3jd5j:
undetectable
5zcoP-3jd5j:
undetectable		 5zcoA-3jd5j:
15.59
5zcoC-3jd5j:
18.80
5zcoP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 5zcoC-3jd5j:
undetectable
5zcoN-3jd5j:
undetectable
5zcoP-3jd5j:
undetectable		 5zcoC-3jd5j:
18.80
5zcoN-3jd5j:
15.59
5zcoP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.11A 5zcpA-3jd5j:
undetectable
5zcpC-3jd5j:
undetectable
5zcpP-3jd5j:
undetectable		 5zcpA-3jd5j:
15.59
5zcpC-3jd5j:
18.80
5zcpP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.12A 5zcqA-3jd5j:
undetectable
5zcqC-3jd5j:
undetectable
5zcqP-3jd5j:
undetectable		 5zcqA-3jd5j:
15.59
5zcqC-3jd5j:
18.80
5zcqP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 TRP j  85
TYR j 203
TRP j 139
HIS j 136
 None
None
None
U  A  59 ( 3.4A)
 1.08A 5zcqN-3jd5j:
undetectable
5zcqP-3jd5j:
undetectable		 5zcqN-3jd5j:
15.59
5zcqP-3jd5j:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 3jd5 28S RIBOSOMAL
PROTEIN S34,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 GLY j 112
ASP j 103
ARG j 101
GLN j 207
 None
None
U  A 881 ( 3.1A)
None
 1.49A 5zrfB-3jd5j:
undetectable		 5zrfB-3jd5j:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 ILE K 100
VAL K 102
ALA K 142
THR K 143
 None
 0.82A 6cduC-3jd5K:
undetectable
6cduD-3jd5K:
undetectable		 6cduC-3jd5K:
20.62
6cduD-3jd5K:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3jd5 28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 ILE Q  13
VAL Q  28
ALA Q  26
THR Q  25
 None
None
None
C  A 120 ( 3.3A)
 0.83A 6cduC-3jd5Q:
undetectable
6cduD-3jd5Q:
undetectable		 6cduC-3jd5Q:
17.65
6cduD-3jd5Q:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 ILE K 100
VAL K 102
ALA K 142
THR K 143
 None
 0.90A 6cduD-3jd5K:
undetectable
6cduE-3jd5K:
undetectable		 6cduD-3jd5K:
20.62
6cduE-3jd5K:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3jd5 28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 ILE Q  13
VAL Q  28
ALA Q  26
THR Q  25
 None
None
None
C  A 120 ( 3.3A)
 0.78A 6cduD-3jd5Q:
undetectable
6cduE-3jd5Q:
undetectable		 6cduD-3jd5Q:
17.65
6cduE-3jd5Q:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3jd5 28S RIBOSOMAL
PROTEIN S11,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 ALA K 142
THR K 143
ILE K 100
VAL K 102
 None
 0.85A 6cduF-3jd5K:
undetectable
6cduJ-3jd5K:
undetectable		 6cduF-3jd5K:
20.62
6cduJ-3jd5K:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3jd5 28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
(Bos
taurus) 		4 / 7 ALA Q  26
THR Q  25
ILE Q  13
VAL Q  28
 None
C  A 120 ( 3.3A)
None
None
 0.83A 6cduF-3jd5Q:
undetectable
6cduJ-3jd5Q:
undetectable		 6cduF-3jd5Q:
17.65
6cduJ-3jd5Q:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBP_B_ADNB404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3jd5 28S RIBOSOMAL
PROTEIN S31,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL
PENTATRICOPEPTIDE
REPEAT
DOMAIN-CONTAINING
PROTEIN 3,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus;
Bos
taurus) 		5 / 12 ILE h 306
HIS o 136
PRO o 135
SER k 164
SER k 160
 None
 1.41A 6fbpA-3jd5h:
undetectable
6fbpB-3jd5h:
undetectable		 6fbpA-3jd5h:
15.19
6fbpB-3jd5h:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 3jd5 28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLY Q  19
VAL Q  28
ASP Q  53
VAL Q  64
GLY Q  61
 C  A 130 ( 4.8A)
None
None
None
None
 0.96A 6gneA-3jd5Q:
undetectable		 6gneA-3jd5Q:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 3jd5 28S RIBOSOMAL
PROTEIN S17,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLY Q  19
VAL Q  28
ASP Q  53
VAL Q  64
GLY Q  61
 C  A 130 ( 4.8A)
None
None
None
None
 0.98A 6gneB-3jd5Q:
undetectable		 6gneB-3jd5Q:
15.13