SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 MET A 218
ALA A 214
TYR A 395
ILE A 275
 None
 1.05A 1upfA-3jq0A:
undetectable		 1upfA-3jq0A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 MET A 218
ALA A 214
TYR A 395
ILE A 275
 None
 1.12A 1upfC-3jq0A:
undetectable		 1upfC-3jq0A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_D_URFD999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 4 MET A 218
ALA A 214
TYR A 395
ILE A 275
 None
 1.08A 1upfD-3jq0A:
undetectable		 1upfD-3jq0A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 THR A  48
GLU A 284
HIS A 209
 None
None
GOL  A   3 (-4.7A)
 0.90A 1xwfA-3jq0A:
undetectable		 1xwfA-3jq0A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 SER A 212
HIS A 279
ASP A 388
 None
 0.86A 2oxtA-3jq0A:
undetectable		 2oxtA-3jq0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 HIS A  51
LEU A 135
ILE A 117
GLU A 137
ALA A 138
 None
 1.19A 2yy8A-3jq0A:
undetectable
2yy8B-3jq0A:
undetectable		 2yy8A-3jq0A:
18.45
2yy8B-3jq0A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A 472
SER A 350
PHE A 260
ALA A 424
 None
 0.84A 3ax7A-3jq0A:
undetectable		 3ax7A-3jq0A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A 472
SER A 350
PHE A 260
ALA A 424
 None
 0.90A 3ax9A-3jq0A:
undetectable		 3ax9A-3jq0A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A 472
SER A 350
PHE A 260
ALA A 424
 None
 0.90A 3ax9B-3jq0A:
undetectable		 3ax9B-3jq0A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A 472
SER A 350
PHE A 260
ALA A 424
 None
 0.90A 3ns1L-3jq0A:
undetectable		 3ns1L-3jq0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ILE A 465
PHE A 245
LYS A 220
GLY A 221
 None
 1.13A 3sj0X-3jq0A:
undetectable		 3sj0X-3jq0A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TYR A 490
LEU A  88
ARG A 484
 None
 0.68A 3sufB-3jq0A:
undetectable		 3sufB-3jq0A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 PRO A 391
ILE A  71
TRP A 288
PHE A 264
 None
 1.41A 3topB-3jq0A:
0.2		 3topB-3jq0A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 ILE A 191
SER A 212
TYR A 393
ALA A 223
GLU A 222
 None
 1.43A 3u6tA-3jq0A:
undetectable		 3u6tA-3jq0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ASN A 418
GLU A 416
ILE A 417
ASP A 412
 None
 1.14A 4d33B-3jq0A:
undetectable		 4d33B-3jq0A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ASN A 418
GLU A 416
ILE A 417
ASP A 412
 None
 1.10A 4d39B-3jq0A:
undetectable		 4d39B-3jq0A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ARG A  87
TYR A 103
ASN A  60
 None
 0.94A 4ffwB-3jq0A:
undetectable		 4ffwB-3jq0A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 ALA A 193
ASP A 190
THR A 120
MET A 116
LEU A  50
 None
 1.45A 4kyaA-3jq0A:
undetectable		 4kyaA-3jq0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 ALA A 193
ASP A 190
THR A 120
MET A 116
LEU A  50
 None
 1.45A 4kyaE-3jq0A:
undetectable		 4kyaE-3jq0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 ASN A 343
TYR A 425
ILE A 437
ARG A 471
 None
 1.33A 4o0oA-3jq0A:
undetectable		 4o0oA-3jq0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 LEU A 219
ALA A 143
ILE A 187
ALA A 244
 None
 0.72A 4wboB-3jq0A:
undetectable		 4wboB-3jq0A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 GLU A 222
ARG A 142
LEU A 158
ILE A 187
 None
 0.96A 4xumA-3jq0A:
undetectable		 4xumA-3jq0A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 4 ILE A 392
ARG A 151
TYR A 393
GLU A 222
 None
 1.32A 4zzbD-3jq0A:
3.0		 4zzbD-3jq0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 THR A  48
ALA A  45
THR A  44
TYR A 134
 None
 1.40A 5ecmA-3jq0A:
undetectable		 5ecmA-3jq0A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3jq0 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ARG A 423
PHE A 473
ARG A 394
 None
 0.95A 5y9yA-3jq0A:
undetectable		 5y9yA-3jq0A:
19.69