SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A 399
ALA A 196
ALA A 214
VAL A 395
TYR A 222
 None
 1.34A 1kt4A-3jq1A:
undetectable		 1kt4A-3jq1A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 GLU A 264
ARG A 332
PHE A 251
PHE A 449
ALA A 393
 None
 1.44A 1wygA-3jq1A:
undetectable		 1wygA-3jq1A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ALA A  75
GLY A  66
GLY A  69
LEU A  56
ILE A 271
 None
 1.11A 1x1aA-3jq1A:
undetectable		 1x1aA-3jq1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 PHE A 136
ASN A 138
GLY A 142
ILE A 121
LEU A 125
 None
 1.10A 1z11D-3jq1A:
undetectable		 1z11D-3jq1A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 THR A 503
PRO A 497
TYR A 109
 None
 0.89A 2dxrA-3jq1A:
undetectable		 2dxrA-3jq1A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 GLU A 143
ALA A 217
PRO A 209
ALA A 213
 None
 1.04A 2ejfA-3jq1A:
undetectable		 2ejfA-3jq1A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 GLU A 143
ALA A 217
PRO A 209
ALA A 213
 None
 1.06A 2zgwB-3jq1A:
undetectable		 2zgwB-3jq1A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A 448
SER A 336
PHE A 251
ALA A 423
 None
 0.96A 3ax7A-3jq1A:
undetectable		 3ax7A-3jq1A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A 448
SER A 336
PHE A 251
ALA A 423
 None
 1.01A 3ax9A-3jq1A:
undetectable		 3ax9A-3jq1A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 PHE A 111
MET A 107
LEU A 103
GLY A  66
GLY A  63
 None
 1.15A 3i5uA-3jq1A:
undetectable		 3i5uA-3jq1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 TYR A 368
PRO A 295
GLU A 377
ARG A 388
 None
 1.23A 3s3oA-3jq1A:
undetectable		 3s3oA-3jq1A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ARG A 148
LEU A 152
ALA A 162
ILE A 185
 None
 0.95A 3wsjB-3jq1A:
undetectable		 3wsjB-3jq1A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ARG A  76
PHE A 494
PRO A 495
 None
 0.86A 3zoaB-3jq1A:
undetectable		 3zoaB-3jq1A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 PRO A 237
LEU A 238
GLN A 211
 None
None
CA  A   5 (-3.2A)
 0.71A 4pevB-3jq1A:
undetectable		 4pevB-3jq1A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 PHE A  82
PRO A 311
VAL A  80
PHE A 450
 None
 1.21A 4w5oA-3jq1A:
undetectable		 4w5oA-3jq1A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 PHE A  82
PRO A 311
VAL A  80
PHE A 450
 None
 1.18A 4z4cA-3jq1A:
undetectable		 4z4cA-3jq1A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 PHE A  82
PRO A 311
VAL A  80
PHE A 450
 None
 1.20A 4z4dA-3jq1A:
undetectable		 4z4dA-3jq1A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 PHE A  82
PRO A 311
VAL A  80
PHE A 450
 None
 1.21A 4z4eA-3jq1A:
undetectable		 4z4eA-3jq1A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ALA A 196
VAL A 140
LEU A 145
GLY A 149
TYR A 151
 None
 1.26A 5igpA-3jq1A:
undetectable		 5igpA-3jq1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 4 GLN A 211
THR A 210
LEU A 235
LEU A 238
 CA  A   5 (-3.2A)
None
None
None
 1.05A 5m5kB-3jq1A:
undetectable		 5m5kB-3jq1A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 ASN A 204
GLU A 268
PHE A 267
TYR A 245
 None
 1.28A 5oh1C-3jq1A:
undetectable		 5oh1C-3jq1A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 PHE A  82
PRO A 311
VAL A  80
PHE A 450
 None
 1.18A 5t7bA-3jq1A:
undetectable		 5t7bA-3jq1A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 VAL A  70
ARG A  73
GLY A  63
TYR A  65
 None
 1.35A 5x80A-3jq1A:
undetectable
5x80B-3jq1A:
undetectable		 5x80A-3jq1A:
15.64
5x80B-3jq1A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 GLY A  63
TYR A  65
VAL A  70
ARG A  73
 None
 1.38A 5x80C-3jq1A:
undetectable
5x80D-3jq1A:
undetectable		 5x80C-3jq1A:
15.64
5x80D-3jq1A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A 164
PHE A 153
GLY A 149
TYR A  65
LEU A  56
 None
 1.10A 5y2tA-3jq1A:
undetectable		 5y2tA-3jq1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A 166
PHE A 153
GLY A 149
TYR A  65
LEU A  56
 None
 1.17A 5y2tA-3jq1A:
undetectable		 5y2tA-3jq1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ARG A 422
PHE A 449
ARG A 391
 None
 1.02A 5y9yA-3jq1A:
undetectable		 5y9yA-3jq1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 3jq1 SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TRP A 320
ILE A 318
ASP A 317
 None
 0.79A 6i0y7-3jq1A:
undetectable		 6i0y7-3jq1A:
6.08