SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.85A 1m8eB-3jq3A:
undetectable		 1m8eB-3jq3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.82A 1nodB-3jq3A:
undetectable		 1nodB-3jq3A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.91A 1qomA-3jq3A:
undetectable		 1qomA-3jq3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 PHE A 240
TYR A 266
TYR A 258
 None
 0.94A 1x70B-3jq3A:
undetectable		 1x70B-3jq3A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 SER A 164
ASP A 197
CYH A 133
 None
 1.17A 2br4E-3jq3A:
undetectable		 2br4E-3jq3A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.80A 2nodB-3jq3A:
undetectable		 2nodB-3jq3A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 196
GLU A 142
SER A 192
 None
 0.60A 2xkkA-3jq3A:
undetectable
2xkkC-3jq3A:
undetectable		 2xkkA-3jq3A:
19.17
2xkkC-3jq3A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 PRO A  12
GLU A  28
TYR A  30
 None
 0.78A 2zmbA-3jq3A:
undetectable		 2zmbA-3jq3A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		4 / 8 LEU A 213
ILE A 214
ARG A 239
GLY A 243
 None
 0.95A 3b9lA-3jq3A:
undetectable		 3b9lA-3jq3A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		4 / 5 ILE A  80
HIS A  84
TYR A  69
GLY A 275
 None
 1.06A 3b9mA-3jq3A:
undetectable		 3b9mA-3jq3A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.76A 3e68A-3jq3A:
undetectable		 3e68A-3jq3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.80A 3e6tB-3jq3A:
undetectable		 3e6tB-3jq3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.89A 3e7iB-3jq3A:
undetectable		 3e7iB-3jq3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		5 / 10 THR A 120
LEU A 244
LEU A  98
GLY A 241
VAL A 337
 None
 1.29A 3lxiA-3jq3A:
undetectable		 3lxiA-3jq3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.87A 3nw2A-3jq3A:
undetectable		 3nw2A-3jq3A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		3 / 3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.89A 3nw2B-3jq3A:
undetectable		 3nw2B-3jq3A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_B_GLYB511_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		4 / 5 GLU A 351
LEU A 289
GLN A 288
LYS A 291
 None
 1.34A 3pgyB-3jq3A:
undetectable		 3pgyB-3jq3A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		5 / 10 THR A 120
LEU A 244
LEU A  98
GLY A 241
VAL A 337
 None
 1.30A 4c9nB-3jq3A:
undetectable		 4c9nB-3jq3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		5 / 9 THR A 120
LEU A 244
LEU A  98
GLY A 241
VAL A 337
 None
 1.28A 4c9pA-3jq3A:
undetectable		 4c9pA-3jq3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		5 / 10 THR A 120
LEU A 244
LEU A  98
GLY A 241
VAL A 337
 None
 1.28A 4c9pB-3jq3A:
undetectable		 4c9pB-3jq3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		4 / 7 PHE A 295
ALA A 316
THR A 309
LEU A 286
 None
 1.09A 4ejgA-3jq3A:
undetectable		 4ejgA-3jq3A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		4 / 7 PHE A  87
HIS A  84
ILE A  80
ASN A 261
 None
 0.95A 4o7gA-3jq3A:
undetectable
4o7gB-3jq3A:
undetectable		 4o7gA-3jq3A:
22.07
4o7gB-3jq3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		4 / 6 PHE A  87
HIS A  84
ILE A  80
ASN A 261
 None
 0.97A 4o7gB-3jq3A:
undetectable		 4o7gB-3jq3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD2_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		4 / 4 GLY A 121
CYH A 268
ARG A 122
GLY A 277
 None
 0.96A 5inzA-3jq3A:
undetectable
5inzC-3jq3A:
undetectable
5inzD-3jq3A:
undetectable		 5inzA-3jq3A:
5.94
5inzC-3jq3A:
5.94
5inzD-3jq3A:
5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		5 / 12 ALA A 201
ILE A 118
PHE A 212
GLY A 241
THR A 146
 None
 1.23A 5jlcA-3jq3A:
undetectable		 5jlcA-3jq3A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3jq3 LOMBRICINE KINASE
(Urechis
caupo) 		4 / 6 PHE A 336
ARG A 334
LEU A 339
ALA A 327
 None
 1.08A 6b89B-3jq3A:
undetectable		 6b89B-3jq3A:
13.92