SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 3jqy POLYSIALIC ACID
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE B  88
PHE B  42
VAL B  77
LEU B  75
SER B  50
 None
 1.20A 2bxeB-3jqyB:
undetectable		 2bxeB-3jqyB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3jqy POLYSIALIC ACID
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 6 VAL B 106
LYS B 105
ILE B  98
ILE B 114
 None
 0.87A 2piwA-3jqyB:
undetectable		 2piwA-3jqyB:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 3jqy POLYSIALIC ACID
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ARG B  87
GLY B 109
HIS B  89
ILE B 135
ASP B 132
 None
 1.36A 3a25A-3jqyB:
undetectable		 3a25A-3jqyB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 3jqy POLYSIALIC ACID
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ARG B  87
GLY B 109
HIS B  89
ILE B 166
ASP B 132
 None
 1.46A 3a25A-3jqyB:
undetectable		 3a25A-3jqyB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 3jqy POLYSIALIC ACID
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 8 ILE B  94
LEU B  75
LEU B  64
PHE B  42
 None
 0.88A 4qopC-3jqyB:
undetectable		 4qopC-3jqyB:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3jqy POLYSIALIC ACID
O-ACETYLTRANSFERASE
(Escherichia
coli) 		3 / 3 VAL B 196
SER B 188
MET B 134
 None
 0.87A 5ikqA-3jqyB:
undetectable		 5ikqA-3jqyB:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3jqy POLYSIALIC ACID
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU B  75
GLY B  96
VAL B 172
VAL B 139
ASP B 138
 None
 1.09A 6bxlB-3jqyB:
undetectable		 6bxlB-3jqyB:
20.63