SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jr1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 6 PHE A 107
ASN A 235
ASN A  73
GLN A 202
 None
 1.20A 1t9uA-3jr1A:
undetectable		 1t9uA-3jr1A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_B_MTXB170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		5 / 10 ALA A 213
LEU A  66
ILE A 111
TYR A 261
THR A 129
 None
 1.37A 1tdrB-3jr1A:
undetectable		 1tdrB-3jr1A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		5 / 12 ALA A 213
LEU A  66
ILE A 111
TYR A 261
THR A 129
 None
 1.31A 2zzaA-3jr1A:
undetectable		 2zzaA-3jr1A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		5 / 11 ALA A 213
LEU A  66
ILE A 111
TYR A 261
THR A 129
 None
 1.31A 2zzaB-3jr1A:
undetectable		 2zzaB-3jr1A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 5 GLU A 252
GLY A 249
TYR A 257
GLU A 220
 None
 1.15A 3w9tA-3jr1A:
undetectable		 3w9tA-3jr1A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 6 GLU A 252
GLY A 249
TYR A 257
GLU A 220
 None
 1.14A 3w9tB-3jr1A:
undetectable		 3w9tB-3jr1A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 5 GLU A 252
GLY A 249
TYR A 257
GLU A 220
 None
 1.14A 3w9tC-3jr1A:
undetectable		 3w9tC-3jr1A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 5 GLU A 252
GLY A 249
TYR A 257
GLU A 220
 None
 1.15A 3w9tD-3jr1A:
undetectable		 3w9tD-3jr1A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 6 GLU A 252
GLY A 249
TYR A 257
GLU A 220
 None
 1.15A 3w9tE-3jr1A:
undetectable		 3w9tE-3jr1A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 6 GLU A 252
GLY A 249
TYR A 257
GLU A 220
 None
 1.15A 3w9tF-3jr1A:
undetectable		 3w9tF-3jr1A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 5 GLU A 252
GLY A 249
TYR A 257
GLU A 220
 None
 1.14A 3w9tG-3jr1A:
undetectable		 3w9tG-3jr1A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 6 ARG A 152
ASP A 139
ASN A 138
TYR A 215
 None
 1.40A 3wfaA-3jr1A:
undetectable
3wfaB-3jr1A:
undetectable		 3wfaA-3jr1A:
16.30
3wfaB-3jr1A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 7 PHE A 107
ILE A 243
TYR A 240
HIS A 115
 None
 1.08A 4g5jA-3jr1A:
5.6		 4g5jA-3jr1A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 5 HIS A 192
ILE A 223
ILE A 111
TYR A 237
 None
 1.23A 5dnvA-3jr1A:
undetectable		 5dnvA-3jr1A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 6 ASN A 138
PHE A 147
TYR A 260
LEU A 191
 None
 1.46A 6a7pB-3jr1A:
undetectable		 6a7pB-3jr1A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		4 / 6 LEU A 251
TYR A 240
ASP A 218
GLU A 220
 None
 1.36A 6djzC-3jr1A:
undetectable		 6djzC-3jr1A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Histophilus
somni) 		3 / 3 GLN A 156
TYR A 267
ASN A 264
 None
 0.81A 6dwdC-3jr1A:
undetectable		 6dwdC-3jr1A:
21.72