SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jrp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 4 HIS A  43
VAL A  38
THR A  26
LEU A  70
 None
 1.37A 1oq5A-3jrpA:
undetectable		 1oq5A-3jrpA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 237
THR A 235
GLU A 283
 None
 0.73A 1pj7A-3jrpA:
undetectable		 1pj7A-3jrpA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		5 / 11 SER A 213
ALA A 211
LEU A 248
SER A 261
LEU A 269
 None
 1.08A 2xn5A-3jrpA:
undetectable		 2xn5A-3jrpA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 141
HIS A 144
LYS A 183
TYR A 187
 None
 1.12A 3eteD-3jrpA:
undetectable
3eteF-3jrpA:
undetectable		 3eteD-3jrpA:
22.97
3eteF-3jrpA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 4 PHE A  66
TYR A 112
ARG A  58
LEU A  70
 None
 1.40A 3sueA-3jrpA:
undetectable		 3sueA-3jrpA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 143
LEU A 196
SER A 152
LEU A 222
VAL A 182
 None
 1.14A 4eckB-3jrpA:
undetectable		 4eckB-3jrpA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 271
SER A 261
LEU A 280
LEU A 248
 None
 1.10A 4n09A-3jrpA:
undetectable		 4n09A-3jrpA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		3 / 3 TRP A  61
ARG A  23
LEU A  49
 None
 0.97A 5dbyA-3jrpA:
undetectable		 5dbyA-3jrpA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 8 SER A 224
ALA A 223
HIS A 203
LEU A 247
 None
 1.20A 5dzkd-3jrpA:
undetectable
5dzkr-3jrpA:
undetectable		 5dzkd-3jrpA:
20.89
5dzkr-3jrpA:
1.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		5 / 11 VAL A1171
GLY A1170
ASP A  14
ALA A  15
LEU A1161
 None
 1.23A 5x6yA-3jrpA:
undetectable		 5x6yA-3jrpA:
19.19