SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jrq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		4 / 7 TYR B 147
VAL B 110
ILE B  89
GLU B 171
 A8S  B   1 (-4.7A)
None
None
A8S  B   1 (-3.4A)
 0.88A 1j96B-3jrqB:
undetectable		 1j96B-3jrqB:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		5 / 8 LEU B  60
PHE B  37
GLU B  36
LEU B  40
HIS B  48
 None
 1.21A 2azxA-3jrqB:
undetectable		 2azxA-3jrqB:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		3 / 3 TYR B  50
VAL B 150
THR B  49
 None
 0.81A 2ygnA-3jrqB:
undetectable		 2ygnA-3jrqB:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		3 / 3 ARG B 155
THR B 133
THR B 205
 None
 0.74A 3k2hB-3jrqB:
undetectable		 3k2hB-3jrqB:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		4 / 7 PHE B  79
ASP B 124
VAL B 108
ARG B 106
 None
 1.02A 3p6hA-3jrqB:
2.3		 3p6hA-3jrqB:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		4 / 7 ARG B 122
VAL B  94
PHE B  79
GLU B  99
 None
 1.34A 4jseA-3jrqB:
undetectable
4jseB-3jrqB:
undetectable		 4jseA-3jrqB:
20.41
4jseB-3jrqB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		4 / 7 PHE B  79
GLU B  99
ARG B 122
VAL B  94
 None
 1.44A 4jseA-3jrqB:
undetectable
4jseB-3jrqB:
undetectable		 4jseA-3jrqB:
20.41
4jseB-3jrqB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		4 / 5 GLN B  83
HIS B  87
ILE B  89
ILE B 111
 None
 1.09A 5dnuA-3jrqB:
undetectable		 5dnuA-3jrqB:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		4 / 5 GLN B  83
HIS B  87
ILE B  89
ILE B 111
 None
 1.07A 5dnvA-3jrqB:
undetectable		 5dnvA-3jrqB:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790
(Arabidopsis
thaliana) 		4 / 5 LEU B 170
VAL B 168
GLU B  36
LEU B  32
 None
 1.13A 5xooB-3jrqB:
undetectable		 5xooB-3jrqB:
18.03