SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jrr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3jrr INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 3
(Mus
musculus) 		5 / 12 ILE A  13
ILE A 122
LEU A 124
VAL A 183
LEU A 223
 None
 1.20A 2qo5A-3jrrA:
undetectable		 2qo5A-3jrrA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3jrr INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 3
(Mus
musculus) 		4 / 7 ARG A 171
VAL A 183
ILE A 221
TYR A 118
 None
 1.11A 2yfbA-3jrrA:
undetectable		 2yfbA-3jrrA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3jrr INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 3
(Mus
musculus) 		4 / 8 GLY A 119
ILE A 122
VAL A 116
VAL A 177
 None
 0.59A 3fi0B-3jrrA:
undetectable		 3fi0B-3jrrA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3jrr INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 3
(Mus
musculus) 		4 / 8 GLY A 119
ILE A 122
VAL A 116
VAL A 177
 None
 0.62A 3fi0G-3jrrA:
undetectable		 3fi0G-3jrrA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3jrr INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 3
(Mus
musculus) 		4 / 8 GLY A 119
ILE A 122
VAL A 116
VAL A 177
 None
 0.58A 3fi0I-3jrrA:
undetectable		 3fi0I-3jrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3jrr INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 3
(Mus
musculus) 		4 / 8 GLY A 119
ILE A 122
VAL A 116
VAL A 177
 None
 0.60A 3fi0Q-3jrrA:
undetectable		 3fi0Q-3jrrA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3jrr INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 3
(Mus
musculus) 		4 / 5 VAL A 178
VAL A 177
ARG A 171
LYS A 220
 None
 1.14A 3rv5A-3jrrA:
undetectable
3rv5B-3jrrA:
undetectable		 3rv5A-3jrrA:
14.64
3rv5B-3jrrA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 3jrr INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 3
(Mus
musculus) 		5 / 12 GLN A  98
GLN A 101
SER A 160
GLY A 156
THR A 155
 None
 1.47A 5oj0A-3jrrA:
undetectable		 5oj0A-3jrrA:
15.45