SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jrt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3jrt INTEGRON CASSETTE
PROTEIN VPC_CASS2
(Vibrio
paracholerae) 		3 / 3 ASP A 165
ARG A 164
ILE A  18
 None
 0.89A 1a4gB-3jrtA:
undetectable		 1a4gB-3jrtA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3jrt INTEGRON CASSETTE
PROTEIN VPC_CASS2
(Vibrio
paracholerae) 		3 / 3 LEU A  37
HIS A  42
LYS A  45
 None
 1.11A 1y7iA-3jrtA:
undetectable		 1y7iA-3jrtA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 3jrt INTEGRON CASSETTE
PROTEIN VPC_CASS2
(Vibrio
paracholerae) 		5 / 12 TYR A  64
ILE A  93
ILE A  99
ILE A 142
TYR A  89
 None
 1.22A 2efjA-3jrtA:
undetectable		 2efjA-3jrtA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 3jrt INTEGRON CASSETTE
PROTEIN VPC_CASS2
(Vibrio
paracholerae) 		4 / 4 LEU A 163
ILE A  85
HIS A  82
VAL A 159
 None
 1.08A 4xyzA-3jrtA:
undetectable		 4xyzA-3jrtA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3jrt INTEGRON CASSETTE
PROTEIN VPC_CASS2
(Vibrio
paracholerae) 		4 / 7 CYH A  61
ILE A  59
LEU A  21
ALA A  24
 None
 0.54A 5hrqE-3jrtA:
undetectable
5hrqF-3jrtA:
undetectable
5hrqJ-3jrtA:
undetectable		 5hrqE-3jrtA:
9.80
5hrqF-3jrtA:
10.92
5hrqJ-3jrtA:
10.92