SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jrv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3jrv PROTEIN K7
(Vaccinia
virus) 		3 / 3 TRP A 112
HIS A  85
MET A  80
 None
 1.34A 1l5qB-3jrvA:
undetectable		 1l5qB-3jrvA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 3jrv PROTEIN K7
(Vaccinia
virus) 		5 / 11 ILE A  26
ILE A  20
TYR A  33
LEU A  57
TYR A  54
 None
 1.05A 2azyA-3jrvA:
undetectable		 2azyA-3jrvA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 3jrv PROTEIN K7
(Vaccinia
virus) 		5 / 11 TYR A  33
LEU A 140
LEU A 148
LEU A 144
ILE A  20
 None
 1.03A 4zowA-3jrvA:
undetectable		 4zowA-3jrvA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3jrv PROTEIN K7
(Vaccinia
virus) 		5 / 12 VAL A  63
ASP A  62
LEU A 131
LEU A  98
LEU A  57
 None
 1.18A 5nd7B-3jrvA:
undetectable		 5nd7B-3jrvA:
15.54