SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3js4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 7 SER A 120
SER A  86
PHE A  82
PHE A 117
 None
 1.17A 1fxvA-3js4A:
undetectable
1fxvB-3js4A:
undetectable		 1fxvA-3js4A:
23.36
1fxvB-3js4A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 7 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.12A 1v55C-3js4A:
undetectable
1v55N-3js4A:
undetectable
1v55P-3js4A:
undetectable		 1v55C-3js4A:
22.68
1v55N-3js4A:
18.43
1v55P-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		5 / 10 ALA A 203
LEU A 132
LEU A 141
LEU A 200
LEU A 161
 None
 1.16A 2xn6A-3js4A:
undetectable
2xn6B-3js4A:
undetectable		 2xn6A-3js4A:
19.65
2xn6B-3js4A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 ASP A  34
THR A  31
TYR A  32
LEU A  39
 None
 1.13A 3ablA-3js4A:
undetectable
3ablC-3js4A:
undetectable
3ablP-3js4A:
undetectable		 3ablA-3js4A:
18.43
3ablC-3js4A:
22.68
3ablP-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.11A 3ablC-3js4A:
undetectable
3ablN-3js4A:
1.2
3ablP-3js4A:
undetectable		 3ablC-3js4A:
22.68
3ablN-3js4A:
18.43
3ablP-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.16A 3asoC-3js4A:
undetectable
3asoN-3js4A:
undetectable
3asoP-3js4A:
undetectable		 3asoC-3js4A:
22.68
3asoN-3js4A:
18.43
3asoP-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		5 / 12 ASP A 150
ILE A  56
GLY A  67
ALA A  75
ALA A  74
 None
 1.01A 3sudC-3js4A:
undetectable		 3sudC-3js4A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		5 / 12 ASP A 150
ILE A  56
GLY A  67
ALA A  75
ALA A  74
 None
 1.06A 3sueA-3js4A:
undetectable		 3sueA-3js4A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.16A 3x2qC-3js4A:
undetectable
3x2qN-3js4A:
undetectable
3x2qP-3js4A:
undetectable		 3x2qC-3js4A:
22.68
3x2qN-3js4A:
18.43
3x2qP-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 6 TYR A 182
HIS A  24
HIS A  80
TYR A  83
 None
FE  A 207 (-3.4A)
FE  A 207 (-3.4A)
None
 1.47A 4df2A-3js4A:
undetectable		 4df2A-3js4A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		5 / 11 LEU A 141
TYR A 134
LEU A  99
LEU A 206
LEU A 200
 None
 1.23A 4wg0I-3js4A:
undetectable
4wg0J-3js4A:
undetectable
4wg0K-3js4A:
undetectable		 4wg0I-3js4A:
5.09
4wg0J-3js4A:
5.09
4wg0K-3js4A:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.11A 5iy5C-3js4A:
undetectable
5iy5N-3js4A:
undetectable
5iy5P-3js4A:
undetectable		 5iy5C-3js4A:
21.80
5iy5N-3js4A:
18.43
5iy5P-3js4A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 5 LEU A  99
PHE A 113
LEU A 141
TRP A 193
 None
 1.31A 5m10A-3js4A:
undetectable		 5m10A-3js4A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 ASP A  34
THR A  31
TYR A  32
LEU A  39
 None
 1.08A 5w97A-3js4A:
undetectable
5w97C-3js4A:
undetectable
5w97c-3js4A:
undetectable		 5w97A-3js4A:
18.43
5w97C-3js4A:
22.68
5w97c-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 7 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.14A 5w97C-3js4A:
undetectable
5w97a-3js4A:
undetectable
5w97c-3js4A:
undetectable		 5w97C-3js4A:
22.68
5w97a-3js4A:
18.43
5w97c-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 ASP A  34
THR A  31
TYR A  32
LEU A  39
 None
 1.13A 5wauA-3js4A:
undetectable
5wauC-3js4A:
undetectable
5wauc-3js4A:
undetectable		 5wauA-3js4A:
18.43
5wauC-3js4A:
22.68
5wauc-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 7 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.13A 5wauC-3js4A:
undetectable
5waua-3js4A:
undetectable
5wauc-3js4A:
undetectable		 5wauC-3js4A:
22.68
5waua-3js4A:
18.43
5wauc-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 ASP A  34
THR A  31
TYR A  32
LEU A  39
 None
 1.06A 5x19A-3js4A:
1.1
5x19C-3js4A:
undetectable
5x19P-3js4A:
undetectable		 5x19A-3js4A:
18.43
5x19C-3js4A:
22.68
5x19P-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 7 ASP A  34
THR A  31
TYR A  32
LEU A  39
 None
 1.03A 5x1bA-3js4A:
undetectable
5x1bC-3js4A:
undetectable
5x1bP-3js4A:
undetectable		 5x1bA-3js4A:
18.43
5x1bC-3js4A:
22.68
5x1bP-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 7 ASP A  34
THR A  31
TYR A  32
LEU A  39
 None
 1.03A 5x1fA-3js4A:
undetectable
5x1fC-3js4A:
undetectable
5x1fP-3js4A:
undetectable		 5x1fA-3js4A:
18.43
5x1fC-3js4A:
22.68
5x1fP-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.13A 5xdqC-3js4A:
undetectable
5xdqN-3js4A:
1.5
5xdqP-3js4A:
undetectable		 5xdqC-3js4A:
22.68
5xdqN-3js4A:
18.43
5xdqP-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.12A 5xdxC-3js4A:
undetectable
5xdxN-3js4A:
1.1
5xdxP-3js4A:
undetectable		 5xdxC-3js4A:
22.07
5xdxN-3js4A:
18.43
5xdxP-3js4A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 7 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.13A 5z84C-3js4A:
undetectable
5z84N-3js4A:
1.3
5z84P-3js4A:
undetectable		 5z84C-3js4A:
22.68
5z84N-3js4A:
18.43
5z84P-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 8 LEU A  39
ASP A  34
THR A  31
TYR A  32
 None
 1.00A 6nknC-3js4A:
undetectable
6nknN-3js4A:
undetectable
6nknP-3js4A:
undetectable		 6nknC-3js4A:
22.68
6nknN-3js4A:
18.43
6nknP-3js4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3js4 SUPEROXIDE DISMUTASE
(Anaplasma
phagocytophilum) 		4 / 7 ASP A  34
THR A  31
TYR A  32
LEU A  39
 None
 0.91A 6nmfA-3js4A:
0.8
6nmfC-3js4A:
undetectable
6nmfP-3js4A:
undetectable		 6nmfA-3js4A:
18.43
6nmfC-3js4A:
22.68
6nmfP-3js4A:
22.68