SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3js6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		5 / 11 LEU A 273
VAL A 277
ILE A 198
VAL A 296
PHE A 316
 None
 1.32A 1gx9A-3js6A:
undetectable		 1gx9A-3js6A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		4 / 8 ILE A 100
PHE A 133
MET A 120
GLY A 119
 None
 1.05A 1os6A-3js6A:
undetectable		 1os6A-3js6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		4 / 7 SER A 187
ILE A 294
ASP A 292
ILE A 288
 None
 0.96A 1yc5A-3js6A:
undetectable		 1yc5A-3js6A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A  66
THR A  80
GLY A  12
ILE A  27
 None
 0.78A 2a1mB-3js6A:
undetectable		 2a1mB-3js6A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A  12
GLY A 298
THR A 297
LEU A 189
HIS A 304
 None
 0.87A 2oxtB-3js6A:
undetectable		 2oxtB-3js6A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A 201
ASP A 199
SER A 122
TYR A 330
 None
 1.37A 2v0gA-3js6A:
undetectable		 2v0gA-3js6A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A   6
ILE A 116
ILE A 152
LEU A 102
VAL A 327
 None
 1.11A 3fpjB-3js6A:
undetectable		 3fpjB-3js6A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ASP A 321
ASP A 190
GLY A  12
ASP A  10
ASP A 169
 None
 1.10A 3prsA-3js6A:
undetectable		 3prsA-3js6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ASP A 321
GLY A 192
GLY A  12
ASP A  10
ASP A 169
 None
 1.11A 3prsA-3js6A:
undetectable		 3prsA-3js6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		5 / 10 LEU A   9
PHE A  66
GLY A 101
ILE A 100
PHE A  92
 None
 1.23A 3qpsA-3js6A:
undetectable		 3qpsA-3js6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A 100
PHE A 133
MET A 120
GLY A 119
 None
 1.14A 3sj0X-3js6A:
undetectable		 3sj0X-3js6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		4 / 5 LEU A 247
GLY A 246
ILE A 225
LYS A 223
 None
 1.20A 4ma8C-3js6A:
undetectable		 4ma8C-3js6A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A 192
ASP A 190
PHE A 281
PHE A 212
HIS A 304
 None
 1.42A 4wh5A-3js6A:
undetectable		 4wh5A-3js6A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 3js6 UNCHARACTERIZED PARM
PROTEIN
(Staphylococcus
aureus) 		5 / 11 ASP A  10
VAL A 114
ILE A 116
THR A 118
ILE A 100
 None
 1.07A 5y80A-3js6A:
undetectable		 5y80A-3js6A:
13.23