SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3js9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 3js9 NUCLEOSIDE
DIPHOSPHATE KINASE
FAMILY PROTEIN
(Babesia
bovis) 		3 / 3 GLU A 121
ALA A 123
SER A 117
 None
 0.62A 1errB-3js9A:
undetectable		 1errB-3js9A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3js9 NUCLEOSIDE
DIPHOSPHATE KINASE
FAMILY PROTEIN
(Babesia
bovis) 		4 / 7 LEU A  61
PHE A  58
MET A  42
THR A  41
 None
 1.03A 3ag4N-3js9A:
undetectable
3ag4W-3js9A:
undetectable		 3ag4N-3js9A:
13.51
3ag4W-3js9A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3js9 NUCLEOSIDE
DIPHOSPHATE KINASE
FAMILY PROTEIN
(Babesia
bovis) 		4 / 8 SER A 117
ALA A 123
HIS A 115
LEU A 129
 None
None
SO4  A 152 (-4.0A)
None
 1.19A 5dzkd-3js9A:
undetectable
5dzkr-3js9A:
undetectable		 5dzkd-3js9A:
19.81
5dzkr-3js9A:
5.26