SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MRQ_A_STRA501_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1)	3jsj	PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR (Streptomyces avermitilis)	5 / 11	LEU A 85 GLU A 92 ILE A 175 LEU A 149 LEU A 153	None	1.28A	1mrqA-3jsjA: undetectable	1mrqA-3jsjA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QEO_B_LLTB261_1 (DEOXYCYTIDINE KINASE)	3jsj	PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR (Streptomyces avermitilis)	4 / 7	GLU A 111 VAL A 108 LEU A 59 LEU A 33	None	0.97A	3qeoB-3jsjA: undetectable	3qeoB-3jsjA: 18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNW_A_T3A501_1 (THYROID HORMONE RECEPTOR ALPHA)	3jsj	PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR (Streptomyces avermitilis)	5 / 12	ALA A 17 ALA A 56 LEU A 59 SER A 58 LEU A 112	None	1.17A	4lnwA-3jsjA: undetectable	4lnwA-3jsjA: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNX_A_T3A502_1 (THYROID HORMONE RECEPTOR ALPHA)	3jsj	PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR (Streptomyces avermitilis)	5 / 12	ALA A 17 ALA A 56 LEU A 59 SER A 58 LEU A 112	None	1.17A	4lnxA-3jsjA: undetectable	4lnxA-3jsjA: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JQ7_B_T0RB705_1 (ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1 ENVELOPE GLYCOPROTEIN 2)	3jsj	PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR (Streptomyces avermitilis)	5 / 7	ARG A 104 VAL A 108 LEU A 112 ALA A 107 LEU A 59	EDO A 191 (-2.6A) None None None None	1.27A	5jq7A-3jsjA: undetectable	5jq7A-3jsjA: 19.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MRQ_A_STRA501_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1","3jsj","PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR","Streptomyces avermitilis",5,"LEU A  85;GLU A  92;ILE A 175;LEU A 149;LEU A 153","None","1.28A","1mrqA-3jsjA:undetectable","1mrqA-3jsjA:23.38"],["3QEO_B_LLTB261_1","DEOXYCYTIDINE KINASE","3jsj","PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR","Streptomyces avermitilis",4,"GLU A 111;VAL A 108;LEU A  59;LEU A  33","None","0.97A","3qeoB-3jsjA:undetectable","3qeoB-3jsjA:18.95"],["4LNW_A_T3A501_1","THYROID HORMONE RECEPTOR ALPHA","3jsj","PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR","Streptomyces avermitilis",5,"ALA A  17;ALA A  56;LEU A  59;SER A  58;LEU A 112","None","1.17A","4lnwA-3jsjA:undetectable","4lnwA-3jsjA:22.51"],["4LNX_A_T3A502_1","THYROID HORMONE RECEPTOR ALPHA","3jsj","PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR","Streptomyces avermitilis",5,"ALA A  17;ALA A  56;LEU A  59;SER A  58;LEU A 112","None","1.17A","4lnxA-3jsjA:undetectable","4lnxA-3jsjA:22.51"],["5JQ7_B_T0RB705_1","ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1;ENVELOPE GLYCOPROTEIN 2","3jsj","PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR","Streptomyces avermitilis",5,"ARG A 104;VAL A 108;LEU A 112;ALA A 107;LEU A  59","EDO A 191 (-2.6A);None;None;None;None","1.27A","5jq7A-3jsjA:undetectable","5jq7A-3jsjA:19.88"]]