SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jte'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3jte RESPONSE REGULATOR
RECEIVER PROTEIN
(Ruminiclostridiu
m
thermocellum) 		4 / 6 ILE A  25
VAL A  80
ILE A  50
ILE A  71
 None
 0.87A 1uwhB-3jteA:
undetectable		 1uwhB-3jteA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3jte RESPONSE REGULATOR
RECEIVER PROTEIN
(Ruminiclostridiu
m
thermocellum) 		3 / 3 THR A  37
LYS A 106
GLU A  38
 None
 1.02A 3ijdB-3jteA:
undetectable		 3ijdB-3jteA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3jte RESPONSE REGULATOR
RECEIVER PROTEIN
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ALA A  33
ASP A  66
ILE A  67
ILE A  71
 None
 0.91A 4kttB-3jteA:
undetectable		 4kttB-3jteA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 3jte RESPONSE REGULATOR
RECEIVER PROTEIN
(Ruminiclostridiu
m
thermocellum) 		3 / 3 ASP A  11
ASP A  10
ASN A  18
 None
 0.85A 4q5mA-3jteA:
undetectable		 4q5mA-3jteA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3jte RESPONSE REGULATOR
RECEIVER PROTEIN
(Ruminiclostridiu
m
thermocellum) 		6 / 9 ALA A 110
ILE A  81
LEU A  83
ILE A  54
ILE A   6
ASN A  28
 None
 1.34A 5nunA-3jteA:
undetectable		 5nunA-3jteA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 3jte RESPONSE REGULATOR
RECEIVER PROTEIN
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A  64
SER A  63
LYS A  58
GLU A  38
LEU A  40
 None
 0.86A 5nwuA-3jteA:
undetectable		 5nwuA-3jteA:
12.90