SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jtn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
3jtn ADAPTER PROTEIN MECA
2

(Bacillus
subtilis)
4 / 7 TYR A  31
GLY A  80
THR A  29
ASN A  81
None
0.71A 2g70A-3jtnA:
undetectable
2g70A-3jtnA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
3jtn ADAPTER PROTEIN MECA
2

(Bacillus
subtilis)
4 / 7 TYR A  31
GLY A  80
THR A  29
ASN A  81
None
0.73A 2g70B-3jtnA:
undetectable
2g70B-3jtnA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3jtn ADAPTER PROTEIN MECA
2

(Bacillus
subtilis)
4 / 8 ALA A  82
ILE A  77
ILE A  13
TYR A  37
None
None
None
IOD  A  98 (-4.7A)
1.02A 2zm8A-3jtnA:
undetectable
2zm8A-3jtnA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3jtn ADAPTER PROTEIN MECA
2

(Bacillus
subtilis)
4 / 8 ALA A  82
ILE A  77
ILE A  13
TYR A  37
None
None
None
IOD  A  98 (-4.7A)
1.02A 2zmaA-3jtnA:
undetectable
2zmaA-3jtnA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
3jtn ADAPTER PROTEIN MECA
2

(Bacillus
subtilis)
5 / 9 ASP A  43
ILE A  25
GLY A  45
VAL A  55
GLY A  51
None
1.35A 4acaB-3jtnA:
undetectable
4acaC-3jtnA:
undetectable
4acaB-3jtnA:
13.39
4acaC-3jtnA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)
3jtn ADAPTER PROTEIN MECA
2

(Bacillus
subtilis)
3 / 3 GLU A  42
ASP A  43
ASP A   2
IOD  A  95 (-4.9A)
None
None
0.73A 4gc9A-3jtnA:
undetectable
4gc9A-3jtnA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
3jtn ADAPTER PROTEIN MECA
2

(Bacillus
subtilis)
5 / 11 ALA A  57
LEU A  56
GLU A  50
ARG A  22
LEU A  20
None
1.09A 4wg0K-3jtnA:
undetectable
4wg0L-3jtnA:
undetectable
4wg0M-3jtnA:
undetectable
4wg0K-3jtnA:
10.00
4wg0L-3jtnA:
10.00
4wg0M-3jtnA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)
3jtn ADAPTER PROTEIN MECA
2

(Bacillus
subtilis)
4 / 5 LEU A  65
TYR A  68
LEU A  70
TYR A  33
None
1.28A 5ki6A-3jtnA:
undetectable
5ki6A-3jtnA:
8.56