SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jts'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.27A 1kifA-3jtsA:
undetectable		 1kifA-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.27A 1kifB-3jtsA:
undetectable		 1kifB-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.27A 1kifC-3jtsA:
undetectable		 1kifC-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.27A 1kifD-3jtsA:
undetectable		 1kifD-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.27A 1kifE-3jtsA:
undetectable		 1kifE-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.27A 1kifF-3jtsA:
undetectable		 1kifF-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.27A 1kifG-3jtsA:
undetectable		 1kifG-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.27A 1kifH-3jtsA:
undetectable		 1kifH-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.24A 1ve9A-3jtsA:
undetectable		 1ve9A-3jtsA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		3 / 3 TRP A 167
GLU A  63
TYR A  59
 None
 0.93A 2a3aA-3jtsA:
undetectable		 2a3aA-3jtsA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 TYR A  85
TYR A 118
ILE A  95
GLY A  83
 None
 1.23A 2du8J-3jtsA:
undetectable		 2du8J-3jtsA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 7 ARG A  48
VAL A  25
ARG A  35
ILE A  23
 None
 0.98A 2yfbA-3jtsA:
undetectable		 2yfbA-3jtsA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.38A 2zj0A-3jtsA:
undetectable		 2zj0A-3jtsA:
18.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		7 / 10 TYR A   9
ILE A  95
TYR A  99
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 0.83A 3uprA-3jtsA:
32.8		 3uprA-3jtsA:
86.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		7 / 10 TYR A   9
ILE A  95
TYR A  99
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 0.78A 3uprC-3jtsA:
33.1		 3uprC-3jtsA:
86.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		6 / 10 TYR A   9
TYR A  99
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 0.78A 3vriA-3jtsA:
32.8
3vriC-3jtsA:
undetectable		 3vriA-3jtsA:
86.96
3vriC-3jtsA:
3.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		7 / 12 TYR A   9
ILE A  95
TYR A  99
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 0.77A 3vrjA-3jtsA:
32.8
3vrjC-3jtsA:
undetectable		 3vrjA-3jtsA:
86.96
3vrjC-3jtsA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.35A 4lvcA-3jtsA:
undetectable		 4lvcA-3jtsA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.34A 4lvcC-3jtsA:
undetectable		 4lvcC-3jtsA:
20.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		3 / 3 PRO A  47
ARG A  48
GLU A  53
 None
 0.99A 5j6hA-3jtsA:
32.7		 5j6hA-3jtsA:
76.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 4 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.36A 5m5kA-3jtsA:
undetectable		 5m5kA-3jtsA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 4 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.36A 5m5kC-3jtsA:
undetectable		 5m5kC-3jtsA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 4 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.33A 5m66B-3jtsA:
undetectable		 5m66B-3jtsA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		3 / 3 THR A 240
THR A 187
LEU A 266
 None
 0.64A 5m66D-3jtsA:
undetectable		 5m66D-3jtsA:
20.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		7 / 10 TYR A   9
ILE A  95
TYR A  99
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 0.80A 5u98A-3jtsA:
32.9		 5u98A-3jtsA:
86.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		5 / 10 TYR A   9
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 1.40A 5u98A-3jtsA:
32.9		 5u98A-3jtsA:
86.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		7 / 10 TYR A   9
ILE A  95
TYR A  99
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 0.79A 5u98D-3jtsA:
32.8		 5u98D-3jtsA:
86.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 4 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.33A 6f3mB-3jtsA:
undetectable		 6f3mB-3jtsA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.36A 6gbnA-3jtsA:
undetectable		 6gbnA-3jtsA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 3jts MHC CLASS I
MAMU-A*02
(Macaca
mulatta) 		4 / 5 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.37A 6gbnD-3jtsA:
undetectable		 6gbnD-3jtsA:
19.30