SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jty'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		5 / 12 THR A 159
GLU A 140
LEU A 156
GLY A  90
GLY A 124
 None
 1.27A 1httB-3jtyA:
undetectable		 1httB-3jtyA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		3 / 3 ASP A 407
ASN A  51
THR A 105
 None
 0.75A 2pymB-3jtyA:
undetectable		 2pymB-3jtyA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		3 / 3 GLY A 153
ASP A 151
SER A 310
 None
 0.59A 3brfA-3jtyA:
undetectable		 3brfA-3jtyA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 8 ASP A 317
SER A 322
PHE A 238
LEU A 148
 None
 1.06A 3m0wE-3jtyA:
undetectable
3m0wF-3jtyA:
undetectable
3m0wG-3jtyA:
undetectable
3m0wH-3jtyA:
undetectable		 3m0wE-3jtyA:
14.21
3m0wF-3jtyA:
14.21
3m0wG-3jtyA:
14.21
3m0wH-3jtyA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 5 LEU A  91
SER A  68
LEU A 156
PRO A 157
 None
 1.29A 3onnA-3jtyA:
undetectable		 3onnA-3jtyA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 5 GLY A  99
GLU A  64
GLY A 101
PRO A 116
 None
 1.01A 3onnA-3jtyA:
undetectable		 3onnA-3jtyA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 7 GLU A 408
GLU A 373
PHE A 406
VAL A 359
 None
 1.09A 4a97A-3jtyA:
undetectable		 4a97A-3jtyA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 7 GLU A 408
GLU A 373
PHE A 406
VAL A 359
 None
 1.08A 4a97D-3jtyA:
undetectable		 4a97D-3jtyA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 8 ARG A 352
GLU A 373
GLU A 375
LYS A 391
 None
 1.21A 4bqfB-3jtyA:
undetectable		 4bqfB-3jtyA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		5 / 12 GLY A 153
ASN A 307
SER A 184
PRO A 143
LEU A 148
 None
 1.08A 4fp9D-3jtyA:
undetectable		 4fp9D-3jtyA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		5 / 12 GLY A 153
ASN A 307
SER A 184
PRO A 143
LEU A 148
 None
 1.07A 4fp9F-3jtyA:
undetectable		 4fp9F-3jtyA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		5 / 12 GLY A 153
ASN A 307
SER A 184
PRO A 143
LEU A 148
 None
 1.03A 4fzvA-3jtyA:
undetectable		 4fzvA-3jtyA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 6 ARG A 154
ARG A 352
GLU A 373
SER A 395
 None
 1.45A 4kr3A-3jtyA:
undetectable		 4kr3A-3jtyA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		3 / 3 ARG A 154
ASP A 151
ARG A 410
 None
 0.71A 4mx0A-3jtyA:
undetectable		 4mx0A-3jtyA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		5 / 12 GLY A 312
GLY A 311
ALA A 321
GLY A 153
ASP A 151
 None
 0.97A 4n09B-3jtyA:
undetectable		 4n09B-3jtyA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		5 / 12 GLY A 312
GLY A 311
ALA A 321
GLY A 153
ASP A 151
 None
 0.96A 4n09D-3jtyA:
undetectable		 4n09D-3jtyA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 7 THR A 159
GLU A 140
GLY A  90
GLY A 124
 None
 0.87A 4rdxA-3jtyA:
undetectable		 4rdxA-3jtyA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3jty BENF-LIKE PORIN
(Pseudomonas
protegens) 		4 / 6 GLU A 213
TYR A 176
GLY A 177
GLY A 178
 None
 0.95A 5x7pB-3jtyA:
undetectable		 5x7pB-3jtyA:
16.52