SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jtz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3jtz INTEGRASE
(Yersinia
pestis) 		4 / 4 LEU A  53
ILE A   8
ARG A   9
TYR A  27
 None
 1.42A 1rk3A-3jtzA:
undetectable		 1rk3A-3jtzA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 3jtz INTEGRASE
(Yersinia
pestis) 		4 / 5 PRO A  57
ILE A   8
ARG A   9
ASP A   5
 None
 1.30A 2rhmB-3jtzA:
undetectable		 2rhmB-3jtzA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 3jtz INTEGRASE
(Yersinia
pestis) 		4 / 5 PRO A  57
ILE A   8
ARG A   9
ASP A   5
 None
 1.28A 2rhmD-3jtzA:
undetectable		 2rhmD-3jtzA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3jtz INTEGRASE
(Yersinia
pestis) 		4 / 5 LEU A  53
ILE A   8
ARG A   9
TYR A  27
 None
 1.46A 2zlcA-3jtzA:
undetectable		 2zlcA-3jtzA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3jtz INTEGRASE
(Yersinia
pestis) 		3 / 3 ARG A  36
ILE A  59
TRP A  38
 None
 1.16A 3nw2B-3jtzA:
undetectable		 3nw2B-3jtzA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3jtz INTEGRASE
(Yersinia
pestis) 		5 / 12 TRP A  38
TYR A  56
ALA A  64
GLY A  25
LEU A  26
 None
 1.31A 4j7xB-3jtzA:
undetectable		 4j7xB-3jtzA:
14.34