SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ju5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		3 / 3 ASN A 277
ARG A 332
ASP A 326
 None
 0.89A 2qe6A-3ju5A:
undetectable		 2qe6A-3ju5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		3 / 3 ASN A 277
ARG A 332
ASP A 326
 None
 0.88A 2qe6B-3ju5A:
undetectable		 2qe6B-3ju5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 5 ILE A  84
HIS A  88
TYR A  73
GLY A 279
 None
 1.21A 3b9mA-3ju5A:
undetectable		 3b9mA-3ju5A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		5 / 12 ARG A 245
GLU A 241
SER A 229
VAL A 121
VAL A 239
 None
 1.33A 3bjmA-3ju5A:
undetectable		 3bjmA-3ju5A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		5 / 12 ARG A 245
GLU A 241
SER A 229
VAL A 121
VAL A 239
 None
 1.39A 3bjmB-3ju5A:
undetectable		 3bjmB-3ju5A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		5 / 12 ARG A 245
GLU A 241
SER A 229
VAL A 121
VAL A 239
 None
 1.24A 3w2tA-3ju5A:
undetectable		 3w2tA-3ju5A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		5 / 12 ARG A 245
GLU A 241
SER A 229
VAL A 121
VAL A 239
 None
 1.26A 3w2tB-3ju5A:
undetectable		 3w2tB-3ju5A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		5 / 12 ARG A 245
GLU A 241
SER A 229
VAL A 121
VAL A 239
 None
 1.44A 4ffwA-3ju5A:
undetectable		 4ffwA-3ju5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		3 / 3 ASP A  69
ARG A 199
THR A  42
 None
 0.88A 4i13A-3ju5A:
undetectable		 4i13A-3ju5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 6 PHE A  91
HIS A  88
ILE A  84
ASN A 265
 None
 0.82A 4o7gB-3ju5A:
undetectable		 4o7gB-3ju5A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		3 / 3 ASP A  69
ARG A 199
THR A  42
 None
 0.89A 4p3rA-3ju5A:
undetectable		 4p3rA-3ju5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 6 TYR A  87
TYR A  73
GLY A  64
ASP A  60
 None
 1.13A 5emlA-3ju5A:
undetectable		 5emlA-3ju5A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHQ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		5 / 12 VAL A  83
TYR A  28
TYR A  34
ALA A  41
ASP A  69
 None
 1.35A 5fhqA-3ju5A:
undetectable		 5fhqA-3ju5A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 8 GLU A 222
SER A 133
GLY A  68
PHE A 192
 None
 0.96A 5flcB-3ju5A:
undetectable		 5flcB-3ju5A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 8 GLU A 222
SER A 133
GLY A  68
PHE A 192
 None
 0.95A 5flcF-3ju5A:
undetectable		 5flcF-3ju5A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		5 / 12 GLY A 195
SER A 133
MET A 197
ASP A  69
GLY A  55
 None
 1.16A 5hikA-3ju5A:
undetectable		 5hikA-3ju5A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 5 LEU A  79
PHE A  76
LEU A  25
PHE A  18
 None
 1.06A 5iy5P-3ju5A:
undetectable
5iy5W-3ju5A:
undetectable		 5iy5P-3ju5A:
20.16
5iy5W-3ju5A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 6 LEU A  79
PHE A  76
LEU A  25
PHE A  18
 None
 1.09A 5w97C-3ju5A:
undetectable
5w97J-3ju5A:
undetectable		 5w97C-3ju5A:
20.42
5w97J-3ju5A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 5 LEU A  79
PHE A  76
LEU A  25
PHE A  18
 None
 1.05A 5x1fC-3ju5A:
undetectable
5x1fJ-3ju5A:
undetectable		 5x1fC-3ju5A:
20.42
5x1fJ-3ju5A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 5 LEU A  79
PHE A  76
LEU A  25
PHE A  18
 None
 1.08A 5xdxC-3ju5A:
undetectable
5xdxJ-3ju5A:
undetectable		 5xdxC-3ju5A:
20.16
5xdxJ-3ju5A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		4 / 5 LEU A  79
PHE A  76
LEU A  25
PHE A  18
 None
 1.12A 5xdxP-3ju5A:
undetectable
5xdxW-3ju5A:
undetectable		 5xdxP-3ju5A:
20.16
5xdxW-3ju5A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3ju5 ARGININE KINASE
(Apostichopus
japonicus) 		5 / 12 ARG A 245
GLU A 241
SER A 229
VAL A 121
VAL A 239
 None
 1.25A 6b1eB-3ju5A:
undetectable		 6b1eB-3ju5A:
18.63