SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ju7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		3 / 3 MET A 246
ASN A  51
GLN A 176
 None
 1.00A 1xoqB-3ju7A:
undetectable		 1xoqB-3ju7A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		4 / 5 SER A  84
SER A 321
THR A 339
ASN A 340
 None
 1.34A 1yvpA-3ju7A:
2.0		 1yvpA-3ju7A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A 164
ALA A 161
ASP A 160
GLY A 198
ILE A 182
 None
None
LLP  A 190 ( 2.8A)
None
None
 0.96A 2hs2A-3ju7A:
undetectable		 2hs2A-3ju7A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A 164
ALA A 161
ASP A 160
GLY A 198
ILE A 182
 None
None
LLP  A 190 ( 2.8A)
None
None
 0.96A 2o4sA-3ju7A:
undetectable		 2o4sA-3ju7A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		4 / 7 ILE A 342
GLY A 276
MET A 273
TRP A 277
 None
 1.21A 2pnjB-3ju7A:
undetectable		 2pnjB-3ju7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		4 / 6 TYR A 135
THR A  90
ALA A  89
PRO A  83
 LLP  A 190 ( 3.8A)
None
LLP  A 190 ( 3.3A)
None
 1.23A 2ql8A-3ju7A:
undetectable
2ql8B-3ju7A:
undetectable		 2ql8A-3ju7A:
15.30
2ql8B-3ju7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		3 / 3 VAL A 117
LYS A 121
HIS A 323
 None
 0.95A 3elzA-3ju7A:
undetectable		 3elzA-3ju7A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		3 / 3 MET A 234
MET A  66
PHE A 186
 None
 0.95A 3gn8A-3ju7A:
undetectable		 3gn8A-3ju7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		5 / 9 GLY A 166
ILE A 183
PHE A  87
PHE A 318
GLY A 139
 None
None
PEG  A 384 ( 4.2A)
None
None
 1.30A 3ko0A-3ju7A:
undetectable
3ko0C-3ju7A:
undetectable		 3ko0A-3ju7A:
16.29
3ko0C-3ju7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		4 / 7 GLY A  98
GLY A  77
MET A 228
PHE A 230
 None
 0.89A 3ko0M-3ju7A:
0.0
3ko0P-3ju7A:
undetectable		 3ko0M-3ju7A:
16.29
3ko0P-3ju7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		5 / 10 GLY A 166
ILE A 183
PHE A  87
PHE A 318
GLY A 139
 None
None
PEG  A 384 ( 4.2A)
None
None
 1.19A 3ko0R-3ju7A:
undetectable
3ko0T-3ju7A:
undetectable		 3ko0R-3ju7A:
16.29
3ko0T-3ju7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		4 / 8 TRP A 119
TYR A 147
ILE A 104
ILE A 122
 None
 1.06A 4afgD-3ju7A:
undetectable
4afgE-3ju7A:
undetectable		 4afgD-3ju7A:
19.39
4afgE-3ju7A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		4 / 8 ILE A 200
ILE A  69
MET A 228
GLY A 229
 None
 0.76A 4hdlA-3ju7A:
undetectable		 4hdlA-3ju7A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		5 / 12 MET A 234
GLY A 195
TYR A 237
GLN A 288
HIS A 187
 None
None
None
PEG  A 384 (-3.5A)
LLP  A 190 (-4.2A)
 1.35A 4xucA-3ju7A:
undetectable		 4xucA-3ju7A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		5 / 12 MET A 234
GLY A 195
TYR A 237
GLN A 288
HIS A 187
 None
None
None
PEG  A 384 (-3.5A)
LLP  A 190 (-4.2A)
 1.38A 4xudA-3ju7A:
2.8		 4xudA-3ju7A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE
(Bacillus
cereus) 		5 / 12 ILE A 346
PHE A  85
LEU A 279
GLN A 280
SER A 140
 None
None
PEG  A 385 ( 4.2A)
None
None
 1.36A 5l8oB-3ju7A:
undetectable		 5l8oB-3ju7A:
15.69