SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_B_KLNB1498_1 (CYTOCHROME P450 3A4)	3jua	TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 (Mus musculus)	5 / 9	LEU A 424 ALA A 285 GLU A 336 GLY A 273 LEU A 277	None	1.30A	2v0mB-3juaA: undetectable	2v0mB-3juaA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IW1_A_ASDA1223_1 (CYTOCHROME P450 CYP125)	3jua	TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 (Mus musculus)	5 / 12	ILE A 388 PHE A 287 VAL A 289 ILE A 243 VAL A 241	None	1.09A	3iw1A-3juaA: undetectable	3iw1A-3juaA: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QDJ_A_SAMA301_0 (MAGNESIUM-PROTOPORPH YRIN O-METHYLTRANSFERASE)	3jua	TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 (Mus musculus)	5 / 12	VAL A 309 PHE A 222 ILE A 354 MET A 219 LEU A 389	None	1.02A	4qdjA-3juaA: undetectable	4qdjA-3juaA: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBS_A_DIFA503_1 (PENTALENIC ACID SYNTHASE)	3jua	TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 (Mus musculus)	4 / 7	ALA A 405 LEU A 274 LEU A 277 ILE A 404	None	0.84A	4ubsA-3juaA: undetectable	4ubsA-3juaA: 18.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2V0M_B_KLNB1498_1","CYTOCHROME P450 3A4","3jua","TRANSCRIPTIONAL ENHANCER FACTOR TEF-3","Mus musculus",5,"LEU A 424;ALA A 285;GLU A 336;GLY A 273;LEU A 277","None","1.30A","2v0mB-3juaA:undetectable","2v0mB-3juaA:19.06"],["3IW1_A_ASDA1223_1","CYTOCHROME P450 CYP125","3jua","TRANSCRIPTIONAL ENHANCER FACTOR TEF-3","Mus musculus",5,"ILE A 388;PHE A 287;VAL A 289;ILE A 243;VAL A 241","None","1.09A","3iw1A-3juaA:undetectable","3iw1A-3juaA:18.43"],["4QDJ_A_SAMA301_0","MAGNESIUM-PROTOPORPHYRIN O-METHYLTRANSFERASE","3jua","TRANSCRIPTIONAL ENHANCER FACTOR TEF-3","Mus musculus",5,"VAL A 309;PHE A 222;ILE A 354;MET A 219;LEU A 389","None","1.02A","4qdjA-3juaA:undetectable","4qdjA-3juaA:22.99"],["4UBS_A_DIFA503_1","PENTALENIC ACID SYNTHASE","3jua","TRANSCRIPTIONAL ENHANCER FACTOR TEF-3","Mus musculus",4,"ALA A 405;LEU A 274;LEU A 277;ILE A 404","None","0.84A","4ubsA-3juaA:undetectable","4ubsA-3juaA:18.36"]]