SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6H_A_CXXA801_1 (TRANSPORTER)	3jui	TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON (Homo sapiens)	5 / 11	LEU A 646 LEU A 676 ILE A 649 PHE A 670 LEU A 601	None	1.28A	2q6hA-3juiA: undetectable	2q6hA-3juiA: 14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F1A_A_SALA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3jui	TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON (Homo sapiens)	4 / 8	LEU A 646 LEU A 710 GLY A 678 ALA A 677	None	0.58A	5f1aA-3juiA: 2.0	5f1aA-3juiA: 13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W8A_A_SAMA300_0 (AUTOINDUCER SYNTHASE)	3jui	TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON (Homo sapiens)	5 / 12	THR A 560 LEU A 561 TYR A 635 PHE A 553 SER A 597	None	1.42A	5w8aA-3juiA: undetectable	5w8aA-3juiA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W8A_A_SAMA300_0 (AUTOINDUCER SYNTHASE)	3jui	TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON (Homo sapiens)	5 / 12	THR A 560 LEU A 561 TYR A 635 SER A 597 GLU A 556	None	1.28A	5w8aA-3juiA: undetectable	5w8aA-3juiA: 21.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Q6H_A_CXXA801_1","TRANSPORTER","3jui","TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON","Homo sapiens",5,"LEU A 646;LEU A 676;ILE A 649;PHE A 670;LEU A 601","None","1.28A","2q6hA-3juiA:undetectable","2q6hA-3juiA:14.72"],["5F1A_A_SALA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3jui","TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON","Homo sapiens",4,"LEU A 646;LEU A 710;GLY A 678;ALA A 677","None","0.58A","5f1aA-3juiA:2.0","5f1aA-3juiA:13.72"],["5W8A_A_SAMA300_0","AUTOINDUCER SYNTHASE","3jui","TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON","Homo sapiens",5,"THR A 560;LEU A 561;TYR A 635;PHE A 553;SER A 597","None","1.42A","5w8aA-3juiA:undetectable","5w8aA-3juiA:21.78"],["5W8A_A_SAMA300_0","AUTOINDUCER SYNTHASE","3jui","TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON","Homo sapiens",5,"THR A 560;LEU A 561;TYR A 635;SER A 597;GLU A 556","None","1.28A","5w8aA-3juiA:undetectable","5w8aA-3juiA:21.78"]]