SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3juj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		3 / 3 THR A  22
THR A  20
PRO A  24
 None
 0.87A 1a7yB-3jujA:
undetectable		 1a7yB-3jujA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 8 SER A  87
ASN A  90
ILE A  91
ARG A 272
 None
 0.86A 1meiA-3jujA:
undetectable		 1meiA-3jujA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		3 / 3 THR A  22
THR A  20
PRO A  24
 None
 0.80A 1qfiB-3jujA:
undetectable		 1qfiB-3jujA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 7 MET A 145
ILE A 204
PRO A 139
GLY A 250
 None
 1.24A 2pnjB-3jujA:
2.9		 2pnjB-3jujA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 8 ILE A 243
VAL A 157
TYR A 152
CYH A 154
 None
 1.15A 2xz5A-3jujA:
undetectable
2xz5C-3jujA:
undetectable		 2xz5A-3jujA:
23.47
2xz5C-3jujA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 8 ILE A 243
VAL A 157
TYR A 152
CYH A 154
 None
 1.14A 2xz5C-3jujA:
undetectable
2xz5D-3jujA:
undetectable		 2xz5C-3jujA:
23.47
2xz5D-3jujA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		5 / 10 PRO A   8
HIS A 110
GLY A 109
GLY A  56
ALA A  10
 None
 1.12A 3pp7B-3jujA:
4.3		 3pp7B-3jujA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 5 ILE A  30
ILE A 134
TYR A  38
GLU A  42
 None
 1.13A 4a99D-3jujA:
undetectable		 4a99D-3jujA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 6 ASN A 200
GLU A 166
TYR A 170
GLU A 160
 None
 1.27A 4mi4A-3jujA:
undetectable		 4mi4A-3jujA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 7 ASN A 200
GLU A 166
TYR A 170
GLU A 160
 None
 1.29A 4mi4A-3jujA:
undetectable
4mi4C-3jujA:
undetectable		 4mi4A-3jujA:
20.82
4mi4C-3jujA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 7 ASN A 200
GLU A 166
TYR A 170
GLU A 160
 None
 1.28A 4mj8C-3jujA:
undetectable		 4mj8C-3jujA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 7 THR A 146
ALA A 125
LEU A 128
ILE A 208
 None
 0.84A 4ubsA-3jujA:
undetectable		 4ubsA-3jujA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 6 ALA A 129
LEU A  35
MET A  27
LEU A  62
 None
 0.99A 4xoyA-3jujA:
undetectable		 4xoyA-3jujA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 6 ALA A 129
LEU A  35
MET A  27
LEU A  62
 None
 0.98A 4xp3A-3jujA:
undetectable		 4xp3A-3jujA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		5 / 12 GLU A 227
GLY A 107
ILE A 228
ILE A 112
HIS A 110
 None
 1.11A 4xucA-3jujA:
undetectable		 4xucA-3jujA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		5 / 12 GLU A 227
GLY A 107
ILE A 228
ILE A 112
HIS A 110
 None
 1.10A 4xudA-3jujA:
undetectable		 4xudA-3jujA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 6 LYS A 169
TYR A 170
GLY A 260
GLU A 263
 None
 1.30A 5emlA-3jujA:
undetectable		 5emlA-3jujA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		5 / 12 ILE A 230
ALA A  10
VAL A  54
GLY A  13
THR A  14
 None
 1.09A 5igiA-3jujA:
undetectable		 5igiA-3jujA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		5 / 12 ILE A 230
ALA A  10
VAL A  54
GLY A  13
THR A  14
 None
 1.10A 5igjA-3jujA:
undetectable		 5igjA-3jujA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		3 / 3 TYR A 268
TYR A  65
SER A  87
 None
 0.98A 5iktB-3jujA:
undetectable		 5iktB-3jujA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		5 / 12 GLY A 107
TYR A 207
VAL A  54
PRO A   8
GLY A  11
 None
 1.29A 6gngA-3jujA:
2.3		 6gngA-3jujA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 4 ASP A 130
ILE A  36
PRO A  34
LEU A  35
 None
 1.26A 6mkeB-3jujA:
undetectable		 6mkeB-3jujA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)
(Helicobacter
pylori) 		4 / 4 ASP A 130
ILE A  36
PRO A  34
LEU A  35
 None
 1.18A 6mkeA-3jujA:
undetectable		 6mkeA-3jujA:
16.58