SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		4 / 7 HIS A  42
GLY A  71
LEU A  78
ALA A  74
 None
 0.87A 1dmaA-3jupA:
undetectable		 1dmaA-3jupA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		5 / 9 SER A 127
PHE A  45
GLY A  66
ILE A  64
PHE A 141
 None
 1.42A 2dr6A-3jupA:
0.0		 2dr6A-3jupA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		4 / 6 PHE A 128
ILE A  91
PHE A 100
PHE A 130
 None
 1.11A 4fgkA-3jupA:
undetectable		 4fgkA-3jupA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		4 / 7 PHE A 124
HIS A 126
TYR A  30
ARG A  41
 AKD  A 500 ( 4.7A)
None
None
None
 1.40A 4o7gA-3jupA:
undetectable
4o7gB-3jupA:
undetectable		 4o7gA-3jupA:
20.50
4o7gB-3jupA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		4 / 8 PHE A 128
ILE A 135
PHE A 141
GLY A  52
 None
None
None
AKD  A 500 ( 4.7A)
 0.97A 4qogA-3jupA:
undetectable
4qogB-3jupA:
undetectable		 4qogA-3jupA:
22.09
4qogB-3jupA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		4 / 8 ARG A 117
PRO A  82
GLY A 108
ASP A  83
 None
 0.72A 5kf8A-3jupA:
undetectable		 5kf8A-3jupA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		4 / 8 ARG A 117
PRO A  82
GLY A 108
ASP A  83
 None
 0.68A 5kgpA-3jupA:
undetectable		 5kgpA-3jupA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		4 / 8 ARG A 117
PRO A  82
GLY A 108
ASP A  83
 None
 0.62A 5kgpB-3jupA:
undetectable		 5kgpB-3jupA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B
(Burkholderia
lata) 		4 / 8 LEU A  53
MET A 142
ASN A 122
ILE A 110
 AKD  A 500 ( 4.2A)
None
None
None
 0.91A 5mzjA-3jupA:
undetectable		 5mzjA-3jupA:
16.00