SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3juy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		6 / 12 TYR B 179
GLN B 232
PHE B 241
VAL B  37
ALA B  97
TRP B 117
 None
 0.61A 1h8sA-3juyB:
23.0		 1h8sA-3juyB:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		4 / 7 TYR B  95
TYR B 179
PRO B 187
TYR B 230
 None
 0.45A 2oldA-3juyB:
6.3
2oldB-3juyB:
18.3		 2oldA-3juyB:
25.75
2oldB-3juyB:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		5 / 7 TYR B 179
HIS B 181
PRO B 187
TYR B 230
TYR B  95
 None
 0.39A 2oldA-3juyB:
6.3
2oldB-3juyB:
18.3		 2oldA-3juyB:
25.75
2oldB-3juyB:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		4 / 7 TYR B 179
HIS B 181
PRO B 187
TYR B  95
 None
 0.67A 2ombC-3juyB:
13.9
2ombD-3juyB:
14.2		 2ombC-3juyB:
25.75
2ombD-3juyB:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		4 / 7 TYR B 179
HIS B 181
PRO B 187
TYR B 230
 None
 0.32A 2ombC-3juyB:
13.9
2ombD-3juyB:
14.2		 2ombC-3juyB:
25.75
2ombD-3juyB:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		4 / 7 VAL B 116
TRP B 117
ASN B 111
GLY B 100
 None
 1.13A 3kmoB-3juyB:
undetectable		 3kmoB-3juyB:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		5 / 11 ALA B  79
ALA B  72
VAL B  34
ALA B  24
SER B   7
 None
 0.94A 3mg0K-3juyB:
undetectable
3mg0L-3juyB:
undetectable		 3mg0K-3juyB:
22.64
3mg0L-3juyB:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		4 / 8 THR B 217
SER B 206
THR B 215
SER B 208
 None
 0.98A 5l4eA-3juyB:
undetectable
5l4eB-3juyB:
undetectable
5l4eC-3juyB:
undetectable
5l4eD-3juyB:
undetectable
5l4eE-3juyB:
undetectable		 5l4eA-3juyB:
19.21
5l4eB-3juyB:
19.21
5l4eC-3juyB:
19.21
5l4eD-3juyB:
19.21
5l4eE-3juyB:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		5 / 9 LEU B 247
ALA B 227
PHE B 226
VAL B 221
ILE B 218
 None
 1.21A 5om2A-3juyB:
undetectable
5om2B-3juyB:
undetectable		 5om2A-3juyB:
16.13
5om2B-3juyB:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3juy 3B3 SINGLE CHAIN
VARIANT HIV-1
ANTIBODY
(Homo
sapiens) 		3 / 3 ARG B 197
ILE B 201
SER B 202
 None
 0.77A 5zw2A-3juyB:
undetectable		 5zw2A-3juyB:
19.44