SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3jv1 P22 PROTEIN
(Trypanosoma
brucei) 		5 / 12 LEU A 190
GLU A  99
LEU A 130
MET A 134
LEU A 103
 None
 1.13A 1g50B-3jv1A:
undetectable		 1g50B-3jv1A:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3jv1 P22 PROTEIN
(Trypanosoma
brucei) 		5 / 11 LEU A 190
GLU A  99
LEU A 130
MET A 134
LEU A 103
 None
 1.12A 1g50C-3jv1A:
undetectable		 1g50C-3jv1A:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3jv1 P22 PROTEIN
(Trypanosoma
brucei) 		3 / 3 ILE A  75
ASP A  82
PHE A  90
 None
 0.61A 1uwjB-3jv1A:
undetectable		 1uwjB-3jv1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3jv1 P22 PROTEIN
(Trypanosoma
brucei) 		3 / 3 TRP A  79
ALA A 192
VAL A 195
 None
 0.81A 2izqA-3jv1A:
undetectable
2izqB-3jv1A:
undetectable		 2izqA-3jv1A:
5.71
2izqB-3jv1A:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3jv1 P22 PROTEIN
(Trypanosoma
brucei) 		3 / 3 ALA A 192
VAL A 195
TRP A  79
 None
 0.83A 3l8lA-3jv1A:
undetectable
3l8lB-3jv1A:
undetectable		 3l8lA-3jv1A:
5.71
3l8lB-3jv1A:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3jv1 P22 PROTEIN
(Trypanosoma
brucei) 		4 / 8 TRP A  79
THR A  80
THR A  91
GLN A 104
 None
 1.36A 5tzoA-3jv1A:
undetectable		 5tzoA-3jv1A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3jv1 P22 PROTEIN
(Trypanosoma
brucei) 		4 / 8 TRP A  79
THR A  80
THR A  91
GLN A 104
 None
 1.34A 5tzoC-3jv1A:
undetectable		 5tzoC-3jv1A:
19.42