SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.34A 1c9sB-3jv3A:
undetectable
1c9sC-3jv3A:
undetectable
1c9sB-3jv3A:
14.87
1c9sC-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.29A 1c9sC-3jv3A:
undetectable
1c9sD-3jv3A:
undetectable
1c9sC-3jv3A:
14.87
1c9sD-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 1c9sE-3jv3A:
undetectable
1c9sF-3jv3A:
undetectable
1c9sE-3jv3A:
14.87
1c9sF-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 1c9sF-3jv3A:
undetectable
1c9sG-3jv3A:
undetectable
1c9sF-3jv3A:
14.87
1c9sG-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.32A 1c9sJ-3jv3A:
undetectable
1c9sK-3jv3A:
undetectable
1c9sJ-3jv3A:
14.87
1c9sK-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)
3jv3 INTERSECTIN-1
(Mus
musculus)
3 / 3 PHE A1346
LEU A1353
SER A1263
None
0.92A 1e7aA-3jv3A:
undetectable
1e7aA-3jv3A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.32A 1gtfA-3jv3A:
undetectable
1gtfK-3jv3A:
undetectable
1gtfA-3jv3A:
14.87
1gtfK-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 1utdD-3jv3A:
undetectable
1utdE-3jv3A:
undetectable
1utdD-3jv3A:
14.87
1utdE-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.34A 1utdG-3jv3A:
undetectable
1utdH-3jv3A:
undetectable
1utdG-3jv3A:
14.87
1utdH-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 VAL A1177
LEU A1204
THR A1205
THR A1206
VAL A1202
None
0.93A 4e3hA-3jv3A:
undetectable
4e3hA-3jv3A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
3jv3 INTERSECTIN-1
(Mus
musculus)
4 / 7 ASN A1247
GLU A1243
GLU A1242
TYR A1245
None
1.25A 4r87I-3jv3A:
undetectable
4r87I-3jv3A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 11 LEU A1238
LEU A1312
ASN A1285
LEU A1288
LEU A1292
None
1.01A 4wg0C-3jv3A:
undetectable
4wg0D-3jv3A:
undetectable
4wg0E-3jv3A:
undetectable
4wg0C-3jv3A:
4.33
4wg0D-3jv3A:
4.33
4wg0E-3jv3A:
4.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
3jv3 INTERSECTIN-1
(Mus
musculus)
4 / 6 LEU A1249
PRO A1371
GLU A1242
TYR A1245
None
1.29A 4z4gA-3jv3A:
undetectable
4z4gA-3jv3A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)
3jv3 INTERSECTIN-1
(Mus
musculus)
4 / 6 TYR A1322
GLU A1242
ARG A1374
ASN A1285
None
1.28A 4zbqA-3jv3A:
undetectable
4zbqA-3jv3A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5eeuA-3jv3A:
undetectable
5eeuB-3jv3A:
undetectable
5eeuA-3jv3A:
14.87
5eeuB-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5eeuD-3jv3A:
undetectable
5eeuE-3jv3A:
undetectable
5eeuD-3jv3A:
14.87
5eeuE-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 5eeuH-3jv3A:
undetectable
5eeuI-3jv3A:
undetectable
5eeuH-3jv3A:
14.87
5eeuI-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5eeuA-3jv3A:
undetectable
5eeuK-3jv3A:
undetectable
5eeuA-3jv3A:
14.87
5eeuK-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5eevD-3jv3A:
undetectable
5eevE-3jv3A:
undetectable
5eevD-3jv3A:
14.87
5eevE-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5eevH-3jv3A:
undetectable
5eevI-3jv3A:
undetectable
5eevH-3jv3A:
14.87
5eevI-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5eevA-3jv3A:
undetectable
5eevK-3jv3A:
undetectable
5eevA-3jv3A:
14.87
5eevK-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5eewD-3jv3A:
undetectable
5eewE-3jv3A:
undetectable
5eewD-3jv3A:
14.87
5eewE-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 5eewH-3jv3A:
undetectable
5eewI-3jv3A:
undetectable
5eewH-3jv3A:
14.87
5eewI-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5eewA-3jv3A:
undetectable
5eewK-3jv3A:
undetectable
5eewA-3jv3A:
14.87
5eewK-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5eexD-3jv3A:
undetectable
5eexE-3jv3A:
undetectable
5eexD-3jv3A:
14.87
5eexE-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 5eexH-3jv3A:
undetectable
5eexI-3jv3A:
undetectable
5eexH-3jv3A:
14.87
5eexI-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5eexA-3jv3A:
undetectable
5eexK-3jv3A:
undetectable
5eexA-3jv3A:
14.87
5eexK-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5eeyD-3jv3A:
undetectable
5eeyE-3jv3A:
undetectable
5eeyD-3jv3A:
14.87
5eeyE-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 5eeyH-3jv3A:
undetectable
5eeyI-3jv3A:
undetectable
5eeyH-3jv3A:
14.87
5eeyI-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5eeyA-3jv3A:
undetectable
5eeyK-3jv3A:
undetectable
5eeyA-3jv3A:
14.87
5eeyK-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5eezD-3jv3A:
undetectable
5eezE-3jv3A:
undetectable
5eezD-3jv3A:
14.87
5eezE-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 5eezH-3jv3A:
undetectable
5eezI-3jv3A:
undetectable
5eezH-3jv3A:
14.87
5eezI-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5eezA-3jv3A:
undetectable
5eezK-3jv3A:
undetectable
5eezA-3jv3A:
14.87
5eezK-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5ef0D-3jv3A:
undetectable
5ef0E-3jv3A:
undetectable
5ef0D-3jv3A:
14.87
5ef0E-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5ef0H-3jv3A:
undetectable
5ef0I-3jv3A:
undetectable
5ef0H-3jv3A:
14.87
5ef0I-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5ef0A-3jv3A:
undetectable
5ef0K-3jv3A:
undetectable
5ef0A-3jv3A:
14.87
5ef0K-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5ef1D-3jv3A:
undetectable
5ef1E-3jv3A:
undetectable
5ef1D-3jv3A:
14.87
5ef1E-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 5ef1H-3jv3A:
undetectable
5ef1I-3jv3A:
undetectable
5ef1H-3jv3A:
14.87
5ef1I-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5ef1A-3jv3A:
undetectable
5ef1K-3jv3A:
undetectable
5ef1A-3jv3A:
14.87
5ef1K-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5ef2D-3jv3A:
undetectable
5ef2E-3jv3A:
undetectable
5ef2D-3jv3A:
14.87
5ef2E-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 5ef2H-3jv3A:
undetectable
5ef2I-3jv3A:
undetectable
5ef2H-3jv3A:
14.87
5ef2I-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5ef2A-3jv3A:
undetectable
5ef2K-3jv3A:
undetectable
5ef2A-3jv3A:
14.87
5ef2K-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.31A 5ef3D-3jv3A:
undetectable
5ef3E-3jv3A:
undetectable
5ef3D-3jv3A:
14.87
5ef3E-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 9 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.30A 5ef3H-3jv3A:
undetectable
5ef3I-3jv3A:
undetectable
5ef3H-3jv3A:
14.87
5ef3I-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3jv3 INTERSECTIN-1
(Mus
musculus)
5 / 10 GLY A1309
HIS A1398
THR A1389
HIS A1396
ILE A1308
None
1.33A 5ef3A-3jv3A:
undetectable
5ef3K-3jv3A:
undetectable
5ef3A-3jv3A:
14.87
5ef3K-3jv3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)
3jv3 INTERSECTIN-1
(Mus
musculus)
4 / 7 VAL A1177
LEU A1204
THR A1205
THR A1206
None
0.78A 5m78A-3jv3A:
undetectable
5m78A-3jv3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)
3jv3 INTERSECTIN-1
(Mus
musculus)
4 / 7 TYR A1378
ILE A1381
ILE A1382
ILE A1308
None
0.94A 5murB-3jv3A:
4.1
5murB-3jv3A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)
3jv3 INTERSECTIN-1
(Mus
musculus)
3 / 3 THR A1253
PRO A1371
ARG A1374
None
0.76A 5nd7B-3jv3A:
undetectable
5nd7B-3jv3A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
3jv3 INTERSECTIN-1
(Mus
musculus)
3 / 3 TYR A1322
ASN A1277
LEU A1281
None
0.84A 6b58A-3jv3A:
undetectable
6b58A-3jv3A:
20.04