SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 3jv4 NUCLEAR FACTOR
NF-KAPPA-B P105
SUBUNIT
(Mus
musculus) 		4 / 6 ILE B 250
SER B 340
ARG B 281
PHE B 311
 None
 1.03A 2q72A-3jv4B:
undetectable		 2q72A-3jv4B:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3jv4 NUCLEAR FACTOR
NF-KAPPA-B P105
SUBUNIT
(Mus
musculus) 		4 / 7 ILE B 250
SER B 340
ARG B 281
PHE B 311
 None
 1.03A 2qb4A-3jv4B:
undetectable		 2qb4A-3jv4B:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3jv4 NUCLEAR FACTOR
NF-KAPPA-B P105
SUBUNIT
(Mus
musculus) 		4 / 8 PHE B 345
ILE B 266
PHE B 282
GLY B 263
 None
 0.89A 2qwxA-3jv4B:
undetectable
2qwxB-3jv4B:
undetectable		 2qwxA-3jv4B:
22.86
2qwxB-3jv4B:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3jv4 NUCLEAR FACTOR
NF-KAPPA-B P105
SUBUNIT
(Mus
musculus) 		4 / 8 PHE B 345
ILE B 266
PHE B 282
GLY B 263
 None
 0.89A 2qx4A-3jv4B:
undetectable
2qx4B-3jv4B:
undetectable		 2qx4A-3jv4B:
22.86
2qx4B-3jv4B:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3jv4 NUCLEAR FACTOR
NF-KAPPA-B P105
SUBUNIT
(Mus
musculus) 		4 / 7 ILE B 309
ARG B 281
THR B 339
LEU B 248
 None
 1.03A 3ablA-3jv4B:
undetectable
3ablJ-3jv4B:
undetectable		 3ablA-3jv4B:
12.80
3ablJ-3jv4B:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3jv4 NUCLEAR FACTOR
NF-KAPPA-B P105
SUBUNIT
(Mus
musculus) 		4 / 8 PHE B 345
ILE B 266
PHE B 282
GLY B 263
 None
 0.91A 4qogA-3jv4B:
undetectable
4qogB-3jv4B:
undetectable		 4qogA-3jv4B:
22.86
4qogB-3jv4B:
22.86