SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 3jv5 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Mus
musculus) 		4 / 6 ILE A 230
SER A 318
ARG A 261
PHE A 289
 None
 0.92A 2q72A-3jv5A:
undetectable		 2q72A-3jv5A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3jv5 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Mus
musculus) 		4 / 6 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 1.13A 5w97C-3jv5A:
undetectable
5w97J-3jv5A:
undetectable		 5w97C-3jv5A:
14.56
5w97J-3jv5A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3jv5 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Mus
musculus) 		4 / 4 VAL A 260
LEU A 309
LEU A 228
ASP A 316
 None
 1.49A 5xv7A-3jv5A:
undetectable		 5xv7A-3jv5A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3jv5 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Mus
musculus) 		4 / 6 TYR A 294
GLU A 264
ASP A 266
GLU A 267
 None
 1.17A 6mn5A-3jv5A:
undetectable		 6mn5A-3jv5A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3jv5 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Mus
musculus) 		4 / 7 TYR A 294
GLU A 264
ASP A 266
GLU A 267
 None
 1.08A 6mn5B-3jv5A:
undetectable		 6mn5B-3jv5A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3jv5 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Mus
musculus) 		4 / 6 TYR A 294
GLU A 264
ASP A 266
GLU A 267
 None
 1.26A 6mn5C-3jv5A:
undetectable		 6mn5C-3jv5A:
18.10