SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 ILE A  28
GLY A  66
VAL A  68
ASP A  82
ALA A 149
 None
 1.32A 1nbhC-3jv7A:
6.8		 1nbhC-3jv7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 1rl8B-3jv7A:
undetectable		 1rl8B-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.77A 1t3rA-3jv7A:
undetectable		 1t3rA-3jv7A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.74A 1t7iA-3jv7A:
undetectable		 1t7iA-3jv7A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.73A 1t7jA-3jv7A:
undetectable		 1t7jA-3jv7A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.73A 2avvE-3jv7A:
undetectable		 2avvE-3jv7A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 4 SER A 251
ASP A 203
ARG A 208
ASP A 207
 NAD  A 503 ( 4.4A)
NAD  A 503 (-2.8A)
NAD  A 503 (-4.0A)
None
 0.90A 2bm9C-3jv7A:
5.2		 2bm9C-3jv7A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.67A 2f80A-3jv7A:
undetectable		 2f80A-3jv7A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 2f80B-3jv7A:
undetectable		 2f80B-3jv7A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.68A 2f81A-3jv7A:
undetectable		 2f81A-3jv7A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.73A 2fxdA-3jv7A:
undetectable		 2fxdA-3jv7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.68A 2hs2A-3jv7A:
undetectable		 2hs2A-3jv7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.79A 2idwB-3jv7A:
undetectable		 2idwB-3jv7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.72A 2ienB-3jv7A:
undetectable		 2ienB-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 2ieoA-3jv7A:
undetectable		 2ieoA-3jv7A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.77A 2nmzA-3jv7A:
undetectable		 2nmzA-3jv7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.71A 2nnkA-3jv7A:
undetectable		 2nnkA-3jv7A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 200
 None
 0.86A 2o4lB-3jv7A:
undetectable		 2o4lB-3jv7A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 3jv7 ADH-A
(Rhodococcus
ruber) 		6 / 12 LEU A 168
GLY A 170
SER A 173
ALA A 175
ALA A 242
VAL A 243
 None
 1.35A 2oc8A-3jv7A:
undetectable		 2oc8A-3jv7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.60A 2pymA-3jv7A:
undetectable		 2pymA-3jv7A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.70A 2pynA-3jv7A:
undetectable		 2pynA-3jv7A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 2q63A-3jv7A:
undetectable		 2q63A-3jv7A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.71A 2q64A-3jv7A:
undetectable		 2q64A-3jv7A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A  56
VAL A  44
MET A  45
LEU A 119
THR A 115
 None
None
None
MPD  A 505 ( 4.3A)
None
 1.06A 2q7kA-3jv7A:
undetectable		 2q7kA-3jv7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.65A 2qakA-3jv7A:
undetectable		 2qakA-3jv7A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.72A 2rkfB-3jv7A:
undetectable		 2rkfB-3jv7A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.72A 2rkgA-3jv7A:
undetectable		 2rkgA-3jv7A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.70A 2rkgB-3jv7A:
undetectable		 2rkgB-3jv7A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 TYR A  54
LEU A  58
SER A 124
ASP A  41
ASP A 153
 MPD  A 505 (-4.6A)
None
None
None
ZN  A 502 (-2.6A)
 1.29A 2vqyA-3jv7A:
undetectable		 2vqyA-3jv7A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 ALA A  85
VAL A  65
GLY A  66
LEU A 143
ALA A 148
 None
 0.83A 2z0yA-3jv7A:
3.2		 2z0yA-3jv7A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3jv7 ADH-A
(Rhodococcus
ruber) 		6 / 9 ALA A 201
VAL A 199
VAL A 180
GLY A 184
GLY A 187
ALA A 212
 None
 1.08A 2z0yA-3jv7A:
3.2		 2z0yA-3jv7A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 ALA A  85
VAL A  65
GLY A  66
LEU A 143
ALA A 148
 None
 0.89A 2z0yB-3jv7A:
2.7		 2z0yB-3jv7A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3jv7 ADH-A
(Rhodococcus
ruber) 		6 / 9 ALA A 201
VAL A 199
VAL A 180
GLY A 184
GLY A 187
ALA A 212
 None
 0.92A 2z0yB-3jv7A:
2.7		 2z0yB-3jv7A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		3 / 3 PRO A 150
LEU A 151
ARG A 309
 None
 0.83A 3aqiA-3jv7A:
3.1		 3aqiA-3jv7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 3bvbB-3jv7A:
undetectable		 3bvbB-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 ALA A 201
GLY A 179
SER A 223
PHE A 244
LEU A 234
 None
NAD  A 503 ( 3.8A)
NAD  A 503 (-2.7A)
None
None
 1.35A 3bxoA-3jv7A:
6.9		 3bxoA-3jv7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 GLY A 179
VAL A 186
ASP A 203
ASP A 205
SER A 223
 NAD  A 503 ( 3.8A)
None
NAD  A 503 (-2.8A)
None
NAD  A 503 (-2.7A)
 1.01A 3cjtC-3jv7A:
8.4		 3cjtC-3jv7A:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 GLY A  91
GLY A  93
GLU A 103
LEU A 112
ASP A 132
 ZN  A 501 ( 4.7A)
ZN  A 501 ( 4.8A)
None
None
None
 1.00A 3ckkA-3jv7A:
5.9		 3ckkA-3jv7A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 PHE A 320
VAL A 343
GLY A  36
ARG A 340
TYR A 329
 None
None
None
NAD  A 503 (-3.2A)
None
 1.17A 3csjB-3jv7A:
undetectable		 3csjB-3jv7A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 3cywA-3jv7A:
undetectable		 3cywA-3jv7A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 PHE A 244
LEU A 191
GLY A 184
GLY A 187
ALA A 201
 None
 1.10A 3dh0B-3jv7A:
7.2		 3dh0B-3jv7A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.68A 3ektA-3jv7A:
undetectable		 3ektA-3jv7A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 3ektC-3jv7A:
undetectable		 3ektC-3jv7A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.70A 3ektD-3jv7A:
undetectable		 3ektD-3jv7A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.80A 3ekvA-3jv7A:
undetectable		 3ekvA-3jv7A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.70A 3el1A-3jv7A:
undetectable		 3el1A-3jv7A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.66A 3gguB-3jv7A:
undetectable		 3gguB-3jv7A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 4 PRO A 150
THR A 152
GLY A 123
THR A  59
 None
 1.11A 3ib1A-3jv7A:
undetectable		 3ib1A-3jv7A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.75A 3jvyA-3jv7A:
undetectable		 3jvyA-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.73A 3jw2A-3jv7A:
undetectable		 3jw2A-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.76A 3jw2B-3jv7A:
undetectable		 3jw2B-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 200
 None
 0.84A 3jw2B-3jv7A:
undetectable		 3jw2B-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.70A 3k4vA-3jv7A:
undetectable		 3k4vA-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.73A 3k4vD-3jv7A:
undetectable		 3k4vD-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.68A 3lzsA-3jv7A:
undetectable		 3lzsA-3jv7A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.65A 3lzsB-3jv7A:
undetectable		 3lzsB-3jv7A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.67A 3lzuA-3jv7A:
undetectable		 3lzuA-3jv7A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.66A 3lzuB-3jv7A:
undetectable		 3lzuB-3jv7A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.75A 3lzvA-3jv7A:
undetectable		 3lzvA-3jv7A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.65A 3mwsA-3jv7A:
undetectable		 3mwsA-3jv7A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.66A 3ndtA-3jv7A:
undetectable		 3ndtA-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.74A 3ndtD-3jv7A:
undetectable		 3ndtD-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.78A 3nduB-3jv7A:
undetectable		 3nduB-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.79A 3nduD-3jv7A:
undetectable		 3nduD-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.67A 3ogqB-3jv7A:
undetectable		 3ogqB-3jv7A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ILE A 200
ILE A 190
 None
 1.02A 3ogqB-3jv7A:
undetectable		 3ogqB-3jv7A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 200
 None
 0.92A 3oxwC-3jv7A:
undetectable		 3oxwC-3jv7A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.80A 3oy4B-3jv7A:
undetectable		 3oy4B-3jv7A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.73A 3pwrA-3jv7A:
undetectable		 3pwrA-3jv7A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
VAL A 176
ILE A 190
 None
 0.92A 3s54A-3jv7A:
undetectable		 3s54A-3jv7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.70A 3s54B-3jv7A:
undetectable		 3s54B-3jv7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 ILE A 315
ALA A 154
THR A 152
VAL A  65
LEU A 143
 None
 1.27A 3s79A-3jv7A:
undetectable		 3s79A-3jv7A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7S_A_EXMA601_1
(CYTOCHROME P450 19A1)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 ILE A 315
ALA A 154
THR A 152
VAL A  65
LEU A 143
 None
 1.25A 3s7sA-3jv7A:
0.0		 3s7sA-3jv7A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 6 VAL A 291
HIS A 265
SER A 267
THR A 292
 None
 1.13A 3tj7A-3jv7A:
undetectable
3tj7B-3jv7A:
undetectable		 3tj7A-3jv7A:
20.57
3tj7B-3jv7A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.72A 3tl9A-3jv7A:
undetectable		 3tl9A-3jv7A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.72A 3u7sA-3jv7A:
undetectable		 3u7sA-3jv7A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 GLY A  36
ALA A  35
GLY A 118
LEU A  30
VAL A  32
 None
 1.02A 3u7sB-3jv7A:
undetectable		 3u7sB-3jv7A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 3ucbB-3jv7A:
undetectable		 3ucbB-3jv7A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 7 PRO A 285
GLY A 287
ALA A 288
ALA A 242
 None
 0.84A 3ur0B-3jv7A:
undetectable		 3ur0B-3jv7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 ALA A 197
GLY A 264
ILE A 231
LEU A 169
PHE A 244
 None
 0.92A 3zosA-3jv7A:
undetectable
3zosB-3jv7A:
undetectable		 3zosA-3jv7A:
23.80
3zosB-3jv7A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		3 / 3 ARG A 333
ARG A 330
ILE A  42
 None
 0.87A 4b7qA-3jv7A:
undetectable		 4b7qA-3jv7A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 6 LYS A   1
ALA A   3
SER A 124
THR A  59
 None
 1.26A 4d7bB-3jv7A:
undetectable		 4d7bB-3jv7A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.76A 4dqbB-3jv7A:
undetectable		 4dqbB-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.73A 4dqcB-3jv7A:
undetectable		 4dqcB-3jv7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.76A 4dqeB-3jv7A:
undetectable		 4dqeB-3jv7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.78A 4dqfB-3jv7A:
undetectable		 4dqfB-3jv7A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.78A 4dqhB-3jv7A:
undetectable		 4dqhB-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 4 PRO A 150
LEU A 151
ILE A 140
ARG A 309
 None
 1.09A 4f4dA-3jv7A:
undetectable		 4f4dA-3jv7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.68A 4hlaA-3jv7A:
undetectable		 4hlaA-3jv7A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_B_1FLB201_1
(TRANSTHYRETIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 4 LYS A   1
ALA A   3
SER A 124
THR A  59
 None
 1.23A 4i89B-3jv7A:
undetectable		 4i89B-3jv7A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.76A 4jecA-3jv7A:
undetectable		 4jecA-3jv7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 ARG A 208
GLY A 216
ALA A 217
ASP A 218
ILE A 162
 NAD  A 503 (-4.0A)
None
None
None
None
 1.12A 4l1aA-3jv7A:
undetectable		 4l1aA-3jv7A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.69A 4ll3B-3jv7A:
undetectable		 4ll3B-3jv7A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.71A 4ll3A-3jv7A:
undetectable		 4ll3A-3jv7A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 4 ILE A 188
VAL A 176
VAL A 199
ARG A 192
 None
 0.93A 4m6tA-3jv7A:
undetectable		 4m6tA-3jv7A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.76A 4njtB-3jv7A:
undetectable		 4njtB-3jv7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.76A 4njtD-3jv7A:
undetectable		 4njtD-3jv7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 PRO A 326
VAL A  16
VAL A 343
ALA A  35
ALA A   3
 None
 1.33A 4oqrA-3jv7A:
undetectable		 4oqrA-3jv7A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.77A 4q1wA-3jv7A:
undetectable		 4q1wA-3jv7A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.80A 4q1xA-3jv7A:
undetectable		 4q1xA-3jv7A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.78A 4q1yA-3jv7A:
undetectable		 4q1yA-3jv7A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.14A 4qvvH-3jv7A:
undetectable		 4qvvH-3jv7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.14A 4qvvV-3jv7A:
undetectable		 4qvvV-3jv7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.14A 4qvyH-3jv7A:
undetectable		 4qvyH-3jv7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 9 ALA A 193
ILE A 315
GLY A 311
ALA A 310
VAL A 304
 None
 1.27A 4r1zA-3jv7A:
undetectable		 4r1zA-3jv7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		3 / 3 ARG A 298
GLU A 303
TYR A  87
 None
 0.83A 4r29D-3jv7A:
undetectable		 4r29D-3jv7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.14A 5d0xV-3jv7A:
undetectable		 5d0xV-3jv7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 5 SER A 289
ALA A 288
HIS A 265
LEU A 168
 None
 1.48A 5dzkb-3jv7A:
undetectable
5dzkp-3jv7A:
undetectable		 5dzkb-3jv7A:
22.03
5dzkp-3jv7A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 5 SER A 289
ALA A 288
HIS A 265
LEU A 168
 None
 1.49A 5dzkc-3jv7A:
undetectable
5dzkq-3jv7A:
undetectable		 5dzkc-3jv7A:
22.03
5dzkq-3jv7A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.70A 5e5jA-3jv7A:
undetectable		 5e5jA-3jv7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.68A 5e5kA-3jv7A:
undetectable		 5e5kA-3jv7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.73A 5e5kB-3jv7A:
undetectable		 5e5kB-3jv7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 8 GLY A 182
HIS A 185
THR A 317
HIS A 316
 NAD  A 503 (-3.6A)
None
None
None
 0.98A 5eevL-3jv7A:
undetectable
5eevV-3jv7A:
undetectable		 5eevL-3jv7A:
11.37
5eevV-3jv7A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 8 GLY A 182
HIS A 185
THR A 317
HIS A 316
 NAD  A 503 (-3.6A)
None
None
None
 0.98A 5eewL-3jv7A:
undetectable
5eewV-3jv7A:
undetectable		 5eewL-3jv7A:
11.37
5eewV-3jv7A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 8 GLY A 182
HIS A 185
THR A 317
HIS A 316
 NAD  A 503 (-3.6A)
None
None
None
 0.98A 5ef3L-3jv7A:
undetectable
5ef3V-3jv7A:
undetectable		 5ef3L-3jv7A:
11.37
5ef3V-3jv7A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 5 ALA A 277
PRO A 293
GLY A  88
LEU A 183
 None
None
None
NAD  A 503 (-3.7A)
 0.99A 5eslA-3jv7A:
undetectable		 5eslA-3jv7A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		3 / 3 GLY A  93
CYH A  98
CYH A  95
 ZN  A 501 ( 4.8A)
ZN  A 501 (-2.3A)
ZN  A 501 (-2.3A)
 0.96A 5inzB-3jv7A:
undetectable		 5inzB-3jv7A:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 3jv7 ADH-A
(Rhodococcus
ruber) 		4 / 6 LYS A   1
ALA A   3
SER A 124
THR A  59
 None
 1.25A 5l4iB-3jv7A:
undetectable		 5l4iB-3jv7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.13A 5l5zH-3jv7A:
undetectable
5l5zI-3jv7A:
undetectable		 5l5zH-3jv7A:
22.74
5l5zI-3jv7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.13A 5l5zV-3jv7A:
undetectable
5l5zW-3jv7A:
undetectable		 5l5zV-3jv7A:
22.74
5l5zW-3jv7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.14A 5lf3H-3jv7A:
undetectable
5lf3I-3jv7A:
undetectable		 5lf3H-3jv7A:
23.23
5lf3I-3jv7A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.14A 5lf3V-3jv7A:
undetectable
5lf3W-3jv7A:
undetectable		 5lf3V-3jv7A:
23.23
5lf3W-3jv7A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 11 THR A  67
ALA A 149
GLY A  64
ALA A  85
THR A 152
 None
 1.12A 5lf7H-3jv7A:
undetectable
5lf7I-3jv7A:
undetectable		 5lf7H-3jv7A:
23.23
5lf7I-3jv7A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3jv7 ADH-A
(Rhodococcus
ruber) 		3 / 3 HIS A  62
GLU A  63
TRP A 295
 ZN  A 502 ( 3.3A)
None
ACY  A 504 ( 3.7A)
 0.94A 5odiD-3jv7A:
undetectable		 5odiD-3jv7A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3jv7 ADH-A
(Rhodococcus
ruber) 		3 / 3 HIS A  62
GLU A  63
TRP A 295
 ZN  A 502 ( 3.3A)
None
ACY  A 504 ( 3.7A)
 1.17A 5odqD-3jv7A:
undetectable		 5odqD-3jv7A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3jv7 ADH-A
(Rhodococcus
ruber) 		3 / 3 HIS A  62
GLU A  63
TRP A 295
 ZN  A 502 ( 3.3A)
None
ACY  A 504 ( 3.7A)
 1.05A 5odrD-3jv7A:
undetectable		 5odrD-3jv7A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 LEU A 211
GLY A 216
ALA A 217
ASP A 218
ILE A 190
 None
 0.83A 5t2zB-3jv7A:
undetectable		 5t2zB-3jv7A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 12 ASP A 218
GLY A 170
ALA A 175
ALA A 242
VAL A 243
 None
 1.06A 6c2mC-3jv7A:
undetectable		 6c2mC-3jv7A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3jv7 ADH-A
(Rhodococcus
ruber) 		5 / 10 ALA A 240
PHE A 244
VAL A 177
ILE A 162
LEU A 169
 None
 1.31A 6h1lA-3jv7A:
undetectable		 6h1lA-3jv7A:
19.58