SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		4 / 6 LEU A 205
ILE A 232
ARG A 233
VAL A 191
 None
 1.06A 1db1A-3jv9A:
undetectable		 1db1A-3jv9A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		5 / 12 PRO A 268
PHE A 165
PRO A 246
THR A 100
ILE A 232
 None
 1.44A 1fm4A-3jv9A:
undetectable		 1fm4A-3jv9A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		4 / 6 GLU A 252
ALA A 247
LEU A 245
VAL A 301
 None
 0.97A 1sn5A-3jv9A:
undetectable		 1sn5A-3jv9A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		4 / 8 GLU A 252
ALA A 247
LEU A 245
VAL A 301
 None
 0.98A 1sn5C-3jv9A:
undetectable		 1sn5C-3jv9A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		4 / 8 MET A 185
PRO A 268
SER A 207
GLY A 265
 None
 1.15A 2qd3A-3jv9A:
undetectable		 2qd3A-3jv9A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		4 / 7 VAL A 101
LEU A 109
MET A 289
ILE A 293
 None
 0.92A 3rfmA-3jv9A:
undetectable		 3rfmA-3jv9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A 105
THR A 129
ILE A  98
LEU A  95
LEU A 136
 None
CL  A 307 (-4.2A)
None
None
None
 1.38A 3vw1B-3jv9A:
undetectable		 3vw1B-3jv9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		3 / 3 LYS A 214
LEU A 211
ALA A 213
 None
 0.67A 4ikiA-3jv9A:
undetectable		 4ikiA-3jv9A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A 124
ILE A 110
LEU A 113
PHE A 303
LEU A 106
 None
 1.05A 4o1zB-3jv9A:
undetectable		 4o1zB-3jv9A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A 106
LEU A 113
LEU A  95
ILE A 293
ALA A 292
 None
 0.76A 4o2bD-3jv9A:
undetectable		 4o2bD-3jv9A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		3 / 3 PRO A 246
LEU A 245
HIS A 234
 None
 0.60A 4pevA-3jv9A:
2.3		 4pevA-3jv9A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		4 / 6 LEU A 160
ASP A 162
GLU A 163
ILE A 144
 None
 0.97A 4xi3C-3jv9A:
undetectable		 4xi3C-3jv9A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A 106
LEU A 113
LEU A  95
ILE A 293
ALA A 292
 None
 0.76A 5eypB-3jv9A:
undetectable		 5eypB-3jv9A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		3 / 3 HIS A 255
SER A 259
LYS A 171
 None
 1.24A 5os7A-3jv9A:
undetectable		 5os7A-3jv9A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A 106
LEU A 113
LEU A  95
ILE A 293
ALA A 292
 None
 0.75A 5xiwB-3jv9A:
undetectable		 5xiwB-3jv9A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A 106
LEU A 113
LEU A  95
ILE A 293
ALA A 292
 None
 0.72A 5xiwD-3jv9A:
undetectable		 5xiwD-3jv9A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A 113
LEU A  95
ILE A 293
ALA A 292
ILE A 145
 None
 1.31A 5xiwD-3jv9A:
undetectable		 5xiwD-3jv9A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Neisseria
meningitidis) 		3 / 3 HIS A 255
SER A 259
LYS A 171
 None
 1.24A 6gmdB-3jv9A:
undetectable		 6gmdB-3jv9A:
18.87