SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		4 / 8 GLY A 182
GLY A 212
TYR A 214
VAL A 246
 None
 0.93A 1dbbH-3jvdA:
undetectable
1dbbL-3jvdA:
undetectable		 1dbbH-3jvdA:
21.16
1dbbL-3jvdA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		5 / 12 LEU A 235
GLY A 265
GLY A 278
VAL A 275
VAL A 261
 None
 0.89A 2f8gB-3jvdA:
undetectable		 2f8gB-3jvdA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		5 / 12 HIS A 325
ALA A 205
ALA A 234
ALA A 199
GLY A 204
 None
 1.22A 2igtC-3jvdA:
4.4		 2igtC-3jvdA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_A_DMOA700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		4 / 6 CYH A 156
PHE A 282
ASP A 267
TYR A 266
 None
 1.35A 2todA-3jvdA:
0.6
2todB-3jvdA:
0.2		 2todA-3jvdA:
23.30
2todB-3jvdA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_B_DMOB700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		4 / 5 ASP A 267
TYR A 266
CYH A 156
PHE A 282
 None
 1.37A 2todA-3jvdA:
0.5
2todB-3jvdA:
0.5		 2todA-3jvdA:
23.30
2todB-3jvdA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_C_DMOC700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		4 / 5 CYH A 156
PHE A 282
ASP A 267
TYR A 266
 None
 1.37A 2todC-3jvdA:
0.4
2todD-3jvdA:
0.6		 2todC-3jvdA:
23.30
2todD-3jvdA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_D_DMOD700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		4 / 5 ASP A 267
TYR A 266
CYH A 156
PHE A 282
 None
 1.37A 2todC-3jvdA:
0.4
2todD-3jvdA:
0.6		 2todC-3jvdA:
23.30
2todD-3jvdA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		5 / 12 HIS A 210
VAL A 226
THR A 208
VAL A 207
VAL A 169
 None
 1.23A 3czvA-3jvdA:
undetectable
3czvB-3jvdA:
undetectable		 3czvA-3jvdA:
20.64
3czvB-3jvdA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		5 / 12 ILE A 196
ALA A 199
ALA A 200
ASN A 176
VAL A 181
 None
 0.87A 3e00A-3jvdA:
undetectable		 3e00A-3jvdA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		3 / 3 GLU A 292
ASP A 299
ASP A  89
 None
 0.78A 3jb2A-3jvdA:
undetectable		 3jb2A-3jvdA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		5 / 12 LEU A 235
GLY A 265
GLY A 278
VAL A 275
VAL A 261
 None
 0.82A 3nu5A-3jvdA:
undetectable		 3nu5A-3jvdA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		5 / 9 LEU A 235
GLY A 265
GLY A 278
VAL A 275
VAL A 261
 None
 0.88A 3oxvA-3jvdA:
undetectable		 3oxvA-3jvdA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		5 / 10 LEU A 235
GLY A 265
GLY A 278
VAL A 275
VAL A 261
 None
 0.90A 3oxwA-3jvdA:
undetectable		 3oxwA-3jvdA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		5 / 10 LEU A 235
GLY A 265
GLY A 278
VAL A 275
VAL A 261
 None
 0.86A 3oxwC-3jvdA:
undetectable		 3oxwC-3jvdA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		4 / 5 VAL A 246
LEU A 235
VAL A 261
PHE A 250
 None
 1.03A 4lb0B-3jvdA:
undetectable		 4lb0B-3jvdA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		3 / 3 GLU A  81
TRP A 271
ASN A  76
 None
 0.78A 5dv4A-3jvdA:
undetectable		 5dv4A-3jvdA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3jvd TRANSCRIPTIONAL
REGULATORS
(Corynebacterium
glutamicum) 		4 / 5 MET A 243
TYR A 272
GLY A 278
GLY A 321
 None
 1.13A 5x7pA-3jvdA:
undetectable		 5x7pA-3jvdA:
13.47