SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3jvg T-CELL SURFACE
GLYCOPROTEIN CD1A1
ANTIGEN
(Gallus
gallus) 		4 / 7 MET A 145
SER A 138
SER A  94
PHE A 110
 UNL  A 283 (-3.6A)
None
None
UNL  A   1 (-4.6A)
 1.15A 1fxvA-3jvgA:
undetectable
1fxvB-3jvgA:
undetectable		 1fxvA-3jvgA:
18.75
1fxvB-3jvgA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 3jvg T-CELL SURFACE
GLYCOPROTEIN CD1A1
ANTIGEN
(Gallus
gallus) 		4 / 4 LYS A  10
LEU A  12
LEU A  28
SER A  38
 None
 1.38A 1tt6A-3jvgA:
undetectable		 1tt6A-3jvgA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3jvg T-CELL SURFACE
GLYCOPROTEIN CD1A1
ANTIGEN
(Gallus
gallus) 		3 / 3 SER A  68
VAL A 154
LEU A 158
 UNL  A   1 (-3.9A)
None
UNL  A   1 (-3.6A)
 0.72A 1yajG-3jvgA:
undetectable		 1yajG-3jvgA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3jvg T-CELL SURFACE
GLYCOPROTEIN CD1A1
ANTIGEN
(Gallus
gallus) 		4 / 8 ILE A  65
PHE A 170
TRP A  52
GLY A  29
 UNL  A   1 ( 4.4A)
None
None
UNL  A   1 ( 3.8A)
 0.99A 4fgjA-3jvgA:
undetectable
4fgjB-3jvgA:
undetectable		 4fgjA-3jvgA:
18.47
4fgjB-3jvgA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3jvg T-CELL SURFACE
GLYCOPROTEIN CD1A1
ANTIGEN
(Gallus
gallus) 		3 / 3 VAL A 234
TYR A 242
GLN A 243
 None
 0.61A 5qgkA-3jvgA:
undetectable		 5qgkA-3jvgA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3jvg T-CELL SURFACE
GLYCOPROTEIN CD1A1
ANTIGEN
(Gallus
gallus) 		3 / 3 VAL A 234
TYR A 242
GLN A 243
 None
 0.59A 5qgrA-3jvgA:
undetectable		 5qgrA-3jvgA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3jvg T-CELL SURFACE
GLYCOPROTEIN CD1A1
ANTIGEN
(Gallus
gallus) 		3 / 3 VAL A 234
TYR A 242
GLN A 243
 None
 0.63A 5qgtA-3jvgA:
undetectable		 5qgtA-3jvgA:
21.00