SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jvi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN5_A_FUNA1356_2 (THYROXINE-BINDING GLOBULIN)	3jvi	PROTEIN TYROSINE PHOSPHATASE (Entamoeba histolytica)	3 / 3	LEU A 139 ARG A 13 ILE A 136	None SO4 A 201 (-4.5A) None	0.64A	2xn5B-3jviA: undetectable	2xn5B-3jviA: 12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_D_9PLD1_1 (CYTOCHROME P450 2A13)	3jvi	PROTEIN TYROSINE PHOSPHATASE (Entamoeba histolytica)	5 / 8	PHE A 84 ALA A 17 PHE A 5 PHE A 112 ALA A 142	None	1.32A	3t3sD-3jviA: undetectable	3t3sD-3jviA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_A_BEZA1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	3jvi	PROTEIN TYROSINE PHOSPHATASE (Entamoeba histolytica)	4 / 6	GLY A 40 THR A 41 SER A 14 VAL A 6	None None SO4 A 201 (-3.2A) None	0.97A	5ewuA-3jviA: undetectable	5ewuA-3jviA: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_B_BEZB1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	3jvi	PROTEIN TYROSINE PHOSPHATASE (Entamoeba histolytica)	4 / 6	GLY A 40 THR A 41 SER A 14 VAL A 6	None None SO4 A 201 (-3.2A) None	1.02A	5ewuB-3jviA: undetectable	5ewuB-3jviA: 18.09

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XN5_A_FUNA1356_2","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","3jvi","PROTEIN TYROSINE PHOSPHATASE","Entamoeba histolytica",3,"LEU A 139;ARG A  13;ILE A 136","None;SO4 A 201 (-4.5A);None","0.64A","2xn5B-3jviA:undetectable","2xn5B-3jviA:12.67"],["3T3S_D_9PLD1_1","CYTOCHROME P450 2A13","3jvi","PROTEIN TYROSINE PHOSPHATASE","Entamoeba histolytica",5,"PHE A  84;ALA A  17;PHE A   5;PHE A 112;ALA A 142","None","1.32A","3t3sD-3jviA:undetectable","3t3sD-3jviA:14.81"],["5EWU_A_BEZA1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","3jvi","PROTEIN TYROSINE PHOSPHATASE","Entamoeba histolytica",4,"GLY A  40;THR A  41;SER A  14;VAL A   6","None;None;SO4 A 201 (-3.2A);None","0.97A","5ewuA-3jviA:undetectable","5ewuA-3jviA:18.09"],["5EWU_B_BEZB1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","3jvi","PROTEIN TYROSINE PHOSPHATASE","Entamoeba histolytica",4,"GLY A  40;THR A  41;SER A  14;VAL A   6","None;None;SO4 A 201 (-3.2A);None","1.02A","5ewuB-3jviA:undetectable","5ewuB-3jviA:18.09"]]