SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jvo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 3jvo GP6
(Escherichia
virus
HK97) 		5 / 12 GLU A  72
GLN A  17
LEU A  64
ILE A   9
LEU A   6
 None
 1.44A 4k38A-3jvoA:
undetectable
4k38D-3jvoA:
undetectable		 4k38A-3jvoA:
13.95
4k38D-3jvoA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3jvo GP6
(Escherichia
virus
HK97) 		4 / 5 ILE A  55
VAL A   8
CYH A  40
HIS A  95
 None
 1.30A 4rzvA-3jvoA:
undetectable		 4rzvA-3jvoA:
16.25