SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jvv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 180
ASP A 145
ASN A 148
GLU A 177
 None
 1.09A 1rjdA-3jvvA:
undetectable		 1rjdA-3jvvA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 180
ASP A 145
ASN A 148
GLU A 177
 None
 1.08A 1rjdB-3jvvA:
4.6		 1rjdB-3jvvA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 180
ASP A 145
ASN A 148
GLU A 177
 None
 1.10A 1rjdC-3jvvA:
4.3		 1rjdC-3jvvA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  50
ILE A  51
ILE A  54
PHE A  96
LEU A  42
 None
 0.88A 1xdkB-3jvvA:
undetectable		 1xdkB-3jvvA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  50
ILE A  51
ILE A  54
PHE A  96
LEU A  42
 None
 0.88A 1xdkF-3jvvA:
undetectable		 1xdkF-3jvvA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 311
VAL A 121
ARG A 117
 None
 0.86A 3b0wB-3jvvA:
undetectable		 3b0wB-3jvvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  51
ALA A  49
LEU A  42
ALA A  22
LEU A  18
 None
 1.12A 3dauA-3jvvA:
undetectable		 3dauA-3jvvA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 312
GLY A 309
VAL A 114
PHE A 115
ILE A 282
 None
 1.02A 3eluA-3jvvA:
undetectable		 3eluA-3jvvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 130
SER A 134
ALA A 278
ALA A 279
CYH A 319
 None
ACP  A 400 (-3.5A)
ACP  A 400 (-3.4A)
None
None
 1.02A 3keeA-3jvvA:
undetectable		 3keeA-3jvvA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ASP A  31
GLY A  14
ALA A  15
ALA A  11
THR A  98
 None
 1.00A 3ucjA-3jvvA:
undetectable		 3ucjA-3jvvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ASP A  31
GLY A  14
ALA A  15
ALA A  11
THR A  98
 None
 1.02A 3ucjB-3jvvA:
undetectable		 3ucjB-3jvvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 217
LEU A 256
GLY A 203
MET A 205
LEU A 228
 None
 1.22A 4kykA-3jvvA:
undetectable
4kykB-3jvvA:
undetectable		 4kykA-3jvvA:
19.06
4kykB-3jvvA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 276
GLY A 133
SER A 134
LEU A 268
 ACP  A 400 (-3.5A)
ACP  A 400 (-3.9A)
ACP  A 400 (-3.5A)
ACP  A 400 (-4.6A)
 1.20A 5bphA-3jvvA:
undetectable		 5bphA-3jvvA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 288
ASN A 291
LEU A 292
 None
 0.41A 5i1nC-3jvvA:
undetectable		 5i1nC-3jvvA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 127
THR A 129
GLY A 130
VAL A 243
ILE A 211
 None
 1.25A 5tuiB-3jvvA:
undetectable		 5tuiB-3jvvA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3jvv TWITCHING MOBILITY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ILE A   3
PHE A  96
PHE A  86
LEU A  24
PRO A  25
 None
 1.05A 5xxiA-3jvvA:
undetectable		 5xxiA-3jvvA:
21.01