SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jwp'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DDS_A_MTXA201_1 (DIHYDROFOLATE REDUCTASE)	3jwp	TRANSCRIPTIONAL REGULATORY PROTEIN SIR2 HOMOLOGUE (Plasmodium falciparum)	5 / 12	ILE A 224 LEU A  26 THR A 229 ILE A 231 THR A  31	None None AMP  A 266 ( 4.9A) None None	1.17A	1ddsA-3jwpA: undetectable	1ddsA-3jwpA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N49_D_RITD401_2 (PROTEASE)	3jwp	TRANSCRIPTIONAL REGULATORY PROTEIN SIR2 HOMOLOGUE (Plasmodium falciparum)	4 / 6	ASP A 109 GLY A 125 ILE A 171 ILE A  73	None	0.93A	1n49D-3jwpA: undetectable	1n49D-3jwpA: 15.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YC5_A_NCAA2001_0 (NAD-DEPENDENT DEACETYLASE)	3jwp	TRANSCRIPTIONAL REGULATORY PROTEIN SIR2 HOMOLOGUE (Plasmodium falciparum)	4 / 7	SER A  32 ILE A  37 ASN A 107 ASP A 109	None	0.37A	1yc5A-3jwpA: 19.9	1yc5A-3jwpA: 31.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UVN_A_ECNA1409_1 (CYTOCHROME P450 130)	3jwp	TRANSCRIPTIONAL REGULATORY PROTEIN SIR2 HOMOLOGUE (Plasmodium falciparum)	5 / 12	THR A  27 THR A 200 GLY A 199 GLY A  30 LEU A 247	None AMP  A 266 (-4.4A) AMP  A 266 (-3.5A) AMP  A 266 (-3.2A) None	1.05A	2uvnA-3jwpA: undetectable	2uvnA-3jwpA: 16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW3_A_TOPA208_1 (DIHYDROFOLATE REDUCTASE)	3jwp	TRANSCRIPTIONAL REGULATORY PROTEIN SIR2 HOMOLOGUE (Plasmodium falciparum)	5 / 10	GLU A  95 LEU A 100 ILE A 198 LEU A 247 THR A 118	None	1.12A	3jw3A-3jwpA: 2.0	3jw3A-3jwpA: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_B_SAMB401_0 (MNMC2)	3jwp	TRANSCRIPTIONAL REGULATORY PROTEIN SIR2 HOMOLOGUE (Plasmodium falciparum)	5 / 12	HIS A  88 GLY A  28 GLY A  30 ALA A 207 LEU A  26	None AMP  A 266 ( 4.0A) AMP  A 266 (-3.2A) None None	1.10A	3vywB-3jwpA: undetectable	3vywB-3jwpA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_C_ADNC301_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	3jwp	TRANSCRIPTIONAL REGULATORY PROTEIN SIR2 HOMOLOGUE (Plasmodium falciparum)	5 / 9	ALA A 251 LEU A 196 LEU A  91 ASN A  86 ILE A 198	None	1.18A	3wdmC-3jwpA: 9.7	3wdmC-3jwpA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_E_Z80E401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	3jwp	TRANSCRIPTIONAL REGULATORY PROTEIN SIR2 HOMOLOGUE (Plasmodium falciparum)	5 / 12	ILE A 121 VAL A 104 ASN A 209 ILE A 189 ALA A 190	None	0.91A	5lg3E-3jwpA: undetectable	5lg3E-3jwpA: 20.41