SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jx8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3jx8 PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		4 / 8 VAL A  66
LEU A  64
TYR A  42
VAL A  80
 None
 0.84A 1fduB-3jx8A:
undetectable		 1fduB-3jx8A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3jx8 PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		5 / 8 VAL A 155
ILE A 130
TYR A  55
PHE A 128
GLN A  57
 None
 1.50A 2weyB-3jx8A:
undetectable		 2weyB-3jx8A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3jx8 PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A 160
VAL A 196
GLY A 194
LEU A 151
PRO A 154
 None
 1.27A 3mecA-3jx8A:
undetectable		 3mecA-3jx8A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3jx8 PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		3 / 3 PRO A 133
THR A 134
LEU A 151
 None
 0.69A 3ttrA-3jx8A:
undetectable		 3ttrA-3jx8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 3jx8 PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A 177
ALA A 199
VAL A 231
ILE A 190
VAL A 196
 None
 0.99A 3ucbB-3jx8A:
undetectable		 3ucbB-3jx8A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 3jx8 PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		5 / 10 LEU A 177
ASP A 213
ILE A 170
VAL A 155
ILE A 175
 None
 1.03A 5kr1A-3jx8A:
undetectable		 5kr1A-3jx8A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 3jx8 PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		4 / 8 ILE A 265
ALA A 239
ILE A 229
GLU A 246
 None
 0.73A 5mvmA-3jx8A:
undetectable
5mvmB-3jx8A:
undetectable		 5mvmA-3jx8A:
14.34
5mvmB-3jx8A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3jx8 PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		3 / 3 ASP A 102
SER A  50
SER A 125
 None
SO4  A   8 (-4.1A)
SO4  A   8 (-2.7A)
 0.66A 6mxtA-3jx8A:
undetectable		 6mxtA-3jx8A:
21.99