SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jx9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		5 / 11 GLN A  19
LEU A  16
SER A 146
LEU A 149
LEU A 125
 None
 1.07A 2xn5A-3jx9A:
undetectable		 2xn5A-3jx9A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		5 / 12 ILE A  68
ALA A  44
LEU A  92
ARG A 120
VAL A  80
 None
 1.08A 3ix9B-3jx9A:
undetectable		 3ix9B-3jx9A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		3 / 3 ARG A 141
ASP A 113
GLN A  19
 None
 0.80A 3lcvB-3jx9A:
undetectable		 3lcvB-3jx9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		5 / 9 ALA A  94
ARG A  98
LEU A  92
ASP A  43
ILE A 108
 None
 1.34A 3wdmA-3jx9A:
6.3		 3wdmA-3jx9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		4 / 6 LEU A  42
TYR A  41
LEU A  55
TYR A  52
 None
 1.13A 4f3tA-3jx9A:
undetectable		 4f3tA-3jx9A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		5 / 12 VAL A  26
LEU A  34
LEU A  55
ALA A 151
PHE A  83
 None
 1.33A 4rtbA-3jx9A:
undetectable		 4rtbA-3jx9A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		3 / 3 LEU A  34
VAL A  77
ASP A  78
 None
 0.57A 4y8wC-3jx9A:
undetectable		 4y8wC-3jx9A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		5 / 10 GLN A  19
LEU A  16
SER A 146
LEU A 149
LEU A 125
 None
 1.13A 4yiaA-3jx9A:
undetectable		 4yiaA-3jx9A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Exiguobacterium
sibiricum) 		4 / 5 LEU A  42
TYR A  41
LEU A  55
TYR A  52
 None
 1.19A 5ki6A-3jx9A:
undetectable		 5ki6A-3jx9A:
12.27