SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jxa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 3jxa CONTACTIN 4
(Mus
musculus) 		5 / 10 PRO A 208
PRO A 146
GLY A 145
LEU A 206
ARG A 129
 None
 1.47A 1h4oA-3jxaA:
undetectable
1h4oB-3jxaA:
undetectable		 1h4oA-3jxaA:
20.00
1h4oB-3jxaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 3jxa CONTACTIN 4
(Mus
musculus) 		5 / 9 PRO A 208
PRO A 146
GLY A 145
LEU A 206
ARG A 129
 None
 1.49A 1h4oD-3jxaA:
undetectable		 1h4oD-3jxaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 3jxa CONTACTIN 4
(Mus
musculus) 		5 / 9 PRO A 208
PRO A 146
GLY A 145
LEU A 206
ARG A 129
 None
 1.47A 1h4oF-3jxaA:
undetectable		 1h4oF-3jxaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3jxa CONTACTIN 4
(Mus
musculus) 		5 / 8 PRO A 208
PRO A 146
GLY A 145
LEU A 206
ARG A 129
 None
 1.48A 1h4oG-3jxaA:
undetectable		 1h4oG-3jxaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 3jxa CONTACTIN 4
(Mus
musculus) 		5 / 9 PRO A 208
PRO A 146
GLY A 145
LEU A 206
ARG A 129
 None
 1.45A 1h4oH-3jxaA:
undetectable		 1h4oH-3jxaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 3jxa CONTACTIN 4
(Mus
musculus) 		5 / 9 PRO A 208
PRO A 146
GLY A 145
LEU A 206
ARG A 129
 None
 1.48A 1hd2A-3jxaA:
undetectable		 1hd2A-3jxaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3jxa CONTACTIN 4
(Mus
musculus) 		5 / 11 GLU A 228
ALA A 249
ILE A 257
ALA A 306
PRO A 225
 None
 1.20A 2admB-3jxaA:
undetectable		 2admB-3jxaA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3jxa CONTACTIN 4
(Mus
musculus) 		5 / 12 TYR A 293
THR A 241
PHE A 231
LEU A 245
PHE A 312
 None
 1.44A 2g72A-3jxaA:
undetectable		 2g72A-3jxaA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 3jxa CONTACTIN 4
(Mus
musculus) 		4 / 5 VAL A  79
TYR A  77
VAL A  69
ASP A  70
 None
 1.16A 2x45A-3jxaA:
undetectable		 2x45A-3jxaA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3jxa CONTACTIN 4
(Mus
musculus) 		4 / 5 VAL A  79
TYR A  77
VAL A  69
ASP A  70
 None
 1.28A 2x45C-3jxaA:
undetectable		 2x45C-3jxaA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3jxa CONTACTIN 4
(Mus
musculus) 		3 / 3 LEU A 214
ARG A 170
ASN A 252
 None
 0.58A 3qxvD-3jxaA:
7.8		 3qxvD-3jxaA:
18.72