SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 7 HIS A 129
LEU A 235
THR A 236
TRP A 246
 None
 0.28A 1am6A-3jxfA:
33.6		 1am6A-3jxfA:
30.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		3 / 3 VAL A 266
VAL A 262
TRP A 130
 None
 0.96A 1av2C-3jxfA:
undetectable
1av2D-3jxfA:
undetectable		 1av2C-3jxfA:
4.61
1av2D-3jxfA:
4.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 HIS A 129
LEU A 235
THR A 236
TRP A 246
 None
 0.31A 1azmA-3jxfA:
32.7		 1azmA-3jxfA:
31.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 PHE A 166
HIS A 129
THR A 236
TRP A 246
 None
 0.78A 1azmA-3jxfA:
32.7		 1azmA-3jxfA:
31.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 HIS A 129
LEU A 235
THR A 236
TRP A 246
 None
 0.27A 1bzmA-3jxfA:
32.8		 1bzmA-3jxfA:
31.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 PHE A 166
HIS A 129
THR A 236
TRP A 246
 None
 0.81A 1bzmA-3jxfA:
32.8		 1bzmA-3jxfA:
31.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
LEU A 176
LEU A 235
THR A 236
TRP A 246
 None
 0.78A 1dmyA-3jxfA:
30.6		 1dmyA-3jxfA:
28.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.26A 1jd0B-3jxfA:
34.2		 1jd0B-3jxfA:
33.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 6 SER A 237
THR A 236
LEU A 176
TRP A 246
 None
 1.08A 1mxdA-3jxfA:
undetectable		 1mxdA-3jxfA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 SER A 237
THR A 236
LEU A 176
TRP A 246
 None
 1.11A 1mxgA-3jxfA:
undetectable		 1mxgA-3jxfA:
19.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 HIS A 129
PHE A 166
VAL A 170
LEU A 235
THR A 236
PRO A 239
 None
 1.15A 1oq5A-3jxfA:
33.6		 1oq5A-3jxfA:
30.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 HIS A 129
VAL A 170
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.72A 1oq5A-3jxfA:
33.6		 1oq5A-3jxfA:
30.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 7 PHE A 128
LEU A 220
PHE A 263
SER A 256
 None
 0.97A 1wrlA-3jxfA:
undetectable
1wrlB-3jxfA:
undetectable		 1wrlA-3jxfA:
16.18
1wrlB-3jxfA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 5 PHE A 128
LEU A 220
PHE A 263
SER A 256
 None
 0.97A 1wrlC-3jxfA:
undetectable		 1wrlC-3jxfA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 7 PHE A 128
LEU A 220
PHE A 263
SER A 256
 None
 0.97A 1wrlE-3jxfA:
undetectable		 1wrlE-3jxfA:
16.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 HIS A 129
HIS A 142
PHE A 166
VAL A 170
LEU A 235
THR A 236
 None
 0.96A 1z9yA-3jxfA:
33.4		 1z9yA-3jxfA:
30.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
VAL A 170
LEU A 235
THR A 236
TRP A 246
 None
 0.94A 1z9yA-3jxfA:
33.4		 1z9yA-3jxfA:
30.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.24A 1zsbA-3jxfA:
33.7		 1zsbA-3jxfA:
29.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
GLU A 141
PHE A 166
LEU A 235
THR A 236
 None
 0.75A 1zsbA-3jxfA:
33.7		 1zsbA-3jxfA:
29.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
LEU A 176
LEU A 235
THR A 236
TRP A 246
 None
 0.42A 2aw1A-3jxfA:
33.4		 2aw1A-3jxfA:
30.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 HIS A 129
LEU A 235
THR A 236
TRP A 246
 None
 0.28A 2gehA-3jxfA:
33.5		 2gehA-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
HIS A 142
PHE A 166
LEU A 235
THR A 236
 None
 0.86A 2pouA-3jxfA:
33.5		 2pouA-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
HIS A 142
PHE A 166
LEU A 235
THR A 236
 None
 0.82A 3bl1A-3jxfA:
33.5		 3bl1A-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.32A 3cajA-3jxfA:
33.6		 3cajA-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 HIS A 129
PHE A 166
LEU A 235
THR A 236
PRO A 239
 None
 0.90A 3cajA-3jxfA:
33.6		 3cajA-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.23A 3dc3A-3jxfA:
33.7		 3dc3A-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.25A 3dcwA-3jxfA:
33.7		 3dcwA-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.28A 3dd0A-3jxfA:
33.7		 3dd0A-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.33A 3f4xA-3jxfA:
33.1		 3f4xA-3jxfA:
30.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.31A 3iaiA-3jxfA:
34.2		 3iaiA-3jxfA:
28.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.32A 3iaiB-3jxfA:
34.3		 3iaiB-3jxfA:
28.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.30A 3iaiC-3jxfA:
34.2		 3iaiC-3jxfA:
28.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.31A 3iaiD-3jxfA:
34.4		 3iaiD-3jxfA:
28.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 9 HIS A 129
LEU A 235
LEU A 106
PHE A 166
VAL A 170
 None
 1.41A 3jwqA-3jxfA:
undetectable		 3jwqA-3jxfA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		3 / 3 VAL A 266
VAL A 262
TRP A 130
 None
 0.83A 3l8lA-3jxfA:
undetectable
3l8lB-3jxfA:
undetectable		 3l8lA-3jxfA:
4.61
3l8lB-3jxfA:
5.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.32A 3mdzA-3jxfA:
34.3		 3mdzA-3jxfA:
29.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 1.24A 3mdzA-3jxfA:
34.3		 3mdzA-3jxfA:
29.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
PHE A 166
LEU A 235
THR A 236
TRP A 246
 None
 0.75A 3ml5A-3jxfA:
34.1		 3ml5A-3jxfA:
31.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 LEU A 217
ASN A 108
ALA A 123
LYS A 122
ILE A 155
 None
 1.12A 3ut5B-3jxfA:
undetectable		 3ut5B-3jxfA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 LEU A 217
ASN A 108
ALA A 123
LYS A 122
ILE A 155
 None
 1.12A 3ut5D-3jxfA:
undetectable		 3ut5D-3jxfA:
19.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 HIS A 129
LEU A 235
THR A 236
TRP A 246
 None
 0.22A 3w6hA-3jxfA:
32.4		 3w6hA-3jxfA:
31.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 9 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.24A 3w6hB-3jxfA:
32.4		 3w6hB-3jxfA:
31.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 LEU A 176
LEU A 235
THR A 236
VAL A 244
TRP A 246
 None
 0.50A 4e3hA-3jxfA:
33.5		 4e3hA-3jxfA:
30.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.22A 4g0cA-3jxfA:
33.6		 4g0cA-3jxfA:
29.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.21A 4g7aA-3jxfA:
29.7		 4g7aA-3jxfA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.23A 4g7aB-3jxfA:
29.7		 4g7aB-3jxfA:
31.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.31A 4k0zA-3jxfA:
33.4		 4k0zA-3jxfA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
LEU A 176
LEU A 235
THR A 236
TRP A 246
 None
 0.52A 4k13A-3jxfA:
33.5		 4k13A-3jxfA:
28.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.26A 4lu3A-3jxfA:
35.5		 4lu3A-3jxfA:
32.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.32A 4m2rA-3jxfA:
33.6		 4m2rA-3jxfA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
VAL A 170
LEU A 235
THR A 236
TRP A 246
 None
 0.72A 4m2vA-3jxfA:
33.7		 4m2vA-3jxfA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
LEU A 176
LEU A 235
THR A 236
TRP A 246
 None
 0.60A 4m2wA-3jxfA:
33.7		 4m2wA-3jxfA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.24A 4uovA-3jxfA:
29.9		 4uovA-3jxfA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.22A 4uovB-3jxfA:
29.9		 4uovB-3jxfA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.23A 4uovC-3jxfA:
29.9		 4uovC-3jxfA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.23A 4uovD-3jxfA:
30.0		 4uovD-3jxfA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.22A 4uovE-3jxfA:
29.9		 4uovE-3jxfA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.23A 4uovF-3jxfA:
30.0		 4uovF-3jxfA:
28.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.24A 4x5sA-3jxfA:
29.3		 4x5sA-3jxfA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.25A 4x5sB-3jxfA:
29.3		 4x5sB-3jxfA:
32.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 6 ILE A 196
VAL A 203
PHE A 263
THR A 101
 None
 0.75A 4xe5A-3jxfA:
undetectable		 4xe5A-3jxfA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.26A 4xiwA-3jxfA:
25.5
4xiwH-3jxfA:
25.2		 4xiwA-3jxfA:
26.24
4xiwH-3jxfA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
VAL A 170
 None
 0.94A 4xiwB-3jxfA:
25.5
4xiwE-3jxfA:
25.4		 4xiwB-3jxfA:
26.24
4xiwE-3jxfA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.34A 4xiwC-3jxfA:
25.5		 4xiwC-3jxfA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.27A 4xiwD-3jxfA:
25.4		 4xiwD-3jxfA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.24A 4xiwE-3jxfA:
25.4		 4xiwE-3jxfA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.21A 4xiwF-3jxfA:
25.2		 4xiwF-3jxfA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 HIS A 129
GLU A 141
LEU A 176
LEU A 235
THR A 236
TRP A 246
 None
 0.62A 4xiwG-3jxfA:
25.1		 4xiwG-3jxfA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.33A 4xiwH-3jxfA:
25.2		 4xiwH-3jxfA:
26.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.37A 4ygfB-3jxfA:
25.8		 4ygfB-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.24A 4ygfD-3jxfA:
25.3		 4ygfD-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.30A 4ygfE-3jxfA:
26.3		 4ygfE-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.38A 4yhaD-3jxfA:
25.1		 4yhaD-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.36A 4yhaE-3jxfA:
26.3		 4yhaE-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.38A 4yhaH-3jxfA:
25.9		 4yhaH-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 HIS A 129
GLU A 141
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.28A 5c8iA-3jxfA:
33.6		 5c8iA-3jxfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.27A 5jn8B-3jxfA:
32.6		 5jn8B-3jxfA:
30.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.27A 5jn8D-3jxfA:
32.2		 5jn8D-3jxfA:
30.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 11 HIS A 129
GLU A 141
LEU A 235
THR A 236
TRP A 246
 None
 0.26A 5jncA-3jxfA:
32.3		 5jncA-3jxfA:
30.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.41A 5tt3A-3jxfA:
26.1		 5tt3A-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 10 HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.38A 5tt3C-3jxfA:
26.3		 5tt3C-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 HIS A 129
LEU A 235
THR A 236
TRP A 246
 None
 0.49A 5tt3F-3jxfA:
25.1		 5tt3F-3jxfA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 8 HIS A 129
LEU A 235
THR A 236
TRP A 246
 None
 0.39A 5tt3H-3jxfA:
25.6		 5tt3H-3jxfA:
30.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		3 / 3 VAL A 248
TYR A 229
GLU A 152
 None
 0.93A 5zmqD-3jxfA:
undetectable
5zmqE-3jxfA:
undetectable		 5zmqD-3jxfA:
24.44
5zmqE-3jxfA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 TRP A  38
HIS A 129
LEU A 235
THR A 236
TRP A 246
 None
 0.57A 6bbsA-3jxfA:
28.6		 6bbsA-3jxfA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 TRP A  38
HIS A 129
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.48A 6bc9A-3jxfA:
33.5		 6bc9A-3jxfA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 HIS A 129
PHE A 166
VAL A 170
LEU A 235
THR A 236
PRO A 239
 None
 1.17A 6bccA-3jxfA:
33.7		 6bccA-3jxfA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		6 / 12 HIS A 129
VAL A 170
LEU A 235
THR A 236
PRO A 239
TRP A 246
 None
 0.69A 6bccA-3jxfA:
33.7		 6bccA-3jxfA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 HIS A 142
PHE A 166
VAL A 170
LEU A 235
THR A 236
 None
 0.86A 6bccA-3jxfA:
33.7		 6bccA-3jxfA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		4 / 6 PHE A 249
VAL A 112
LEU A 218
LEU A 221
 None
 0.98A 6e43D-3jxfA:
undetectable		 6e43D-3jxfA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA
(Homo
sapiens) 		5 / 12 VAL A 170
GLU A 168
ALA A 169
GLY A 174
LEU A 235
 None
 1.13A 6f6iA-3jxfA:
undetectable
6f6iB-3jxfA:
undetectable		 6f6iA-3jxfA:
15.18
6f6iB-3jxfA:
14.93