SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jxo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 3jxo TRKA-N DOMAIN
PROTEIN
(Thermotoga
sp.
RQ2) 		4 / 7 PRO A 187
THR A 191
GLY A 189
LEU A 199
 None
 0.93A 2vl2B-3jxoA:
undetectable		 2vl2B-3jxoA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3jxo TRKA-N DOMAIN
PROTEIN
(Thermotoga
sp.
RQ2) 		4 / 8 ILE A 178
LEU A 199
VAL A 160
GLY A 161
 None
 0.83A 3w1wA-3jxoA:
undetectable		 3w1wA-3jxoA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_A_ACTA202_0
(NITROGEN REGULATORY
PROTEIN P-II)		 3jxo TRKA-N DOMAIN
PROTEIN
(Thermotoga
sp.
RQ2) 		4 / 4 VAL A 183
GLY A 181
ARG A 180
VAL A 185
 None
 1.38A 5d4nA-3jxoA:
2.0
5d4nB-3jxoA:
2.4		 5d4nA-3jxoA:
26.55
5d4nB-3jxoA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3jxo TRKA-N DOMAIN
PROTEIN
(Thermotoga
sp.
RQ2) 		5 / 10 ILE A 178
PRO A 187
LEU A 199
PRO A 170
LEU A 194
 None
 1.16A 5ienB-3jxoA:
undetectable		 5ienB-3jxoA:
23.58