SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jys'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ILE A 257
ILE A 415
ALA A 434
LEU A 441
ILE A 438
 None
 1.12A 1bsxA-3jysA:
undetectable		 1bsxA-3jysA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ILE A 257
ILE A 415
ALA A 434
LEU A 441
ILE A 438
 None
 1.12A 1bsxB-3jysA:
undetectable		 1bsxB-3jysA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 LEU A 263
ALA A 264
GLU A 284
LEU A 270
ILE A 359
 None
 1.28A 1g50A-3jysA:
undetectable		 1g50A-3jysA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ASN A 465
ASP A 468
GLU A 469
ARG A 357
ASP A 448
 None
 1.23A 1s14A-3jysA:
undetectable		 1s14A-3jysA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ASN A 465
ASP A 468
GLU A 469
ARG A 357
ASP A 448
 None
 1.25A 1s14B-3jysA:
undetectable		 1s14B-3jysA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ALA A 422
TYR A 246
ARG A 425
TYR A 167
 None
 1.10A 2ajvH-3jysA:
undetectable
2ajvL-3jysA:
undetectable		 2ajvH-3jysA:
18.99
2ajvL-3jysA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 GLY A 478
GLY A 413
PHE A 271
PHE A 387
 None
 0.98A 2qwxA-3jysA:
undetectable
2qwxB-3jysA:
undetectable		 2qwxA-3jysA:
18.42
2qwxB-3jysA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 LEU A  82
LEU A  81
ILE A 304
ARG A  83
 None
 1.01A 2rlfA-3jysA:
undetectable
2rlfB-3jysA:
undetectable		 2rlfA-3jysA:
6.56
2rlfB-3jysA:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ILE A 179
ALA A 133
ILE A 518
PRO A 519
LEU A 529
 None
 1.13A 2w3mA-3jysA:
undetectable		 2w3mA-3jysA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 THR A 241
ASP A 171
LEU A 196
LEU A 204
ASN A 205
 None
 1.05A 2zw9B-3jysA:
undetectable		 2zw9B-3jysA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TYR A 218
TYR A 261
ILE A 286
 None
 0.84A 3eteA-3jysA:
undetectable
3eteB-3jysA:
undetectable		 3eteA-3jysA:
21.38
3eteB-3jysA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ASN A 465
ASP A 468
GLU A 469
ARG A 357
ASP A 448
 None
 1.28A 3lpsA-3jysA:
undetectable		 3lpsA-3jysA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 PHE A 160
PHE A 410
ALA A 228
LEU A 204
 None
 0.95A 3t3zA-3jysA:
undetectable		 3t3zA-3jysA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 PHE A 160
PHE A 410
ALA A 228
LEU A 204
 None
 0.95A 3t3zB-3jysA:
undetectable		 3t3zB-3jysA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 LEU A 229
LEU A 204
ILE A 207
TRP A 199
 None
 0.99A 4do3B-3jysA:
0.0		 4do3B-3jysA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 PHE A 410
GLN A  89
GLU A  95
ARG A 470
LEU A 229
 None
 1.40A 4k38B-3jysA:
undetectable		 4k38B-3jysA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 GLY A 375
GLU A 378
THR A 379
 None
 0.49A 4kouA-3jysA:
undetectable		 4kouA-3jysA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 LEU A 270
LYS A 283
GLU A 284
TYR A 218
 None
 1.11A 4lb2A-3jysA:
undetectable		 4lb2A-3jysA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 THR A 521
LEU A 169
GLN A  89
LEU A  88
 None
 1.19A 4nc3A-3jysA:
1.9		 4nc3A-3jysA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 TYR A 267
ARG A 357
GLU A 284
VAL A 256
 None
 1.46A 4nkvB-3jysA:
undetectable		 4nkvB-3jysA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLY A 471
GLU A  95
LEU A 484
GLU A 421
ILE A 479
 None
 1.12A 4pb1A-3jysA:
undetectable		 4pb1A-3jysA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 LEU A 229
ALA A 163
ILE A 200
ALA A 252
 None
 0.77A 4wboB-3jysA:
undetectable		 4wboB-3jysA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 ALA A 424
VAL A 423
LYS A 431
GLU A 455
 None
 0.92A 4zbqA-3jysA:
undetectable		 4zbqA-3jysA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 VAL A 515
LEU A 229
MET A 233
 None
 0.89A 5ikrA-3jysA:
undetectable		 5ikrA-3jysA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 GLN A  89
THR A 482
ASP A 171
 None
 0.92A 5k9dA-3jysA:
undetectable		 5k9dA-3jysA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 GLN A  91
ILE A 367
HIS A 338
 None
 0.70A 5z12B-3jysA:
undetectable		 5z12B-3jysA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 LEU A 263
ALA A 264
GLU A 284
LEU A 270
ILE A 359
 None
 1.32A 6cbzB-3jysA:
undetectable		 6cbzB-3jysA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TRP A  86
GLU A 477
GLU A  95
 None
 0.93A 6fhwA-3jysA:
2.5		 6fhwA-3jysA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_2
(GLUCOAMYLASE P)		 3jys SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 4 TRP A  86
GLU A 477
GLU A  95
LEU A 336
 None
 0.92A 6fhwB-3jysA:
0.0		 6fhwB-3jysA:
11.93