SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 6 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 0.98A 1dz4A-3jyyA:
undetectable		 1dz4A-3jyyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 6 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 1.02A 1dz4B-3jyyA:
undetectable		 1dz4B-3jyyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		5 / 12 ILE A  45
VAL A  64
LEU A  14
ASP A  56
PHE A  55
 None
 1.46A 1p5zB-3jyyA:
undetectable		 1p5zB-3jyyA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 7 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 0.98A 1t87A-3jyyA:
undetectable		 1t87A-3jyyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 7 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 0.98A 1t87B-3jyyA:
undetectable		 1t87B-3jyyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 5 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 0.99A 1t88B-3jyyA:
undetectable		 1t88B-3jyyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 5 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 1.01A 2m56A-3jyyA:
undetectable		 2m56A-3jyyA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 6 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 1.06A 2zawA-3jyyA:
undetectable		 2zawA-3jyyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 6 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 1.04A 2zuhA-3jyyA:
undetectable		 2zuhA-3jyyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 6 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 1.04A 2zuiA-3jyyA:
undetectable		 2zuiA-3jyyA:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JZ0_A_CLYA900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		9 / 10 TYR A  27
GLU A  42
TYR A  44
TYR A  75
GLU A  89
HIS A  91
PHE A 104
ILE A 110
MET A 116
 None
MG  A 304 (-2.8A)
None
None
MG  A 304 (-3.1A)
None
None
None
None
 0.56A 3jz0A-3jyyA:
37.3		 3jz0A-3jyyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JZ0_A_CLYA900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		6 / 10 TYR A  27
TYR A  44
TYR A  75
HIS A  91
ILE A 132
MET A 116
 None
 1.35A 3jz0A-3jyyA:
37.3		 3jz0A-3jyyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JZ0_A_CLYA900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		6 / 10 TYR A  44
TYR A  75
GLU A  89
HIS A  91
PHE A 104
SER A 107
 None
None
MG  A 304 (-3.1A)
None
None
None
 1.11A 3jz0A-3jyyA:
37.3		 3jz0A-3jyyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		7 / 8 TYR A  27
GLU A  42
TYR A  44
TYR A  75
GLU A  89
PHE A 104
ILE A 110
 None
MG  A 304 (-2.8A)
None
None
MG  A 304 (-3.1A)
None
None
 0.68A 3jz0B-3jyyA:
36.4		 3jz0B-3jyyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		5 / 8 TYR A  44
TYR A  75
GLU A  89
PHE A 104
SER A 107
 None
None
MG  A 304 (-3.1A)
None
None
 1.25A 3jz0B-3jyyA:
36.4		 3jz0B-3jyyA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 6 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 0.97A 4g3rB-3jyyA:
undetectable		 4g3rB-3jyyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		4 / 7 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 1.05A 4l4gA-3jyyA:
undetectable		 4l4gA-3jyyA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		5 / 12 PHE A  55
PHE A  92
ILE A  21
VAL A  64
VAL A  11
 None
 1.19A 4yfbC-3jyyA:
undetectable		 4yfbC-3jyyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		5 / 12 PHE A  55
PHE A  92
ILE A  21
VAL A  64
VAL A  11
 None
 1.20A 4yfbF-3jyyA:
0.1		 4yfbF-3jyyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		5 / 12 PHE A  55
PHE A  92
ILE A  21
VAL A  64
VAL A  11
 None
 1.19A 4yfbI-3jyyA:
undetectable		 4yfbI-3jyyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		5 / 12 PHE A  55
PHE A  92
ILE A  21
VAL A  64
VAL A  11
 None
 1.18A 4yfbL-3jyyA:
undetectable		 4yfbL-3jyyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE
(Enterococcus
faecium) 		5 / 12 ILE A  81
TYR A  71
THR A  77
HIS A  91
PHE A  90
 None
 1.49A 6j20A-3jyyA:
undetectable		 6j20A-3jyyA:
19.73